Ukuqothulwa ngokweqile kuyigama elisetshenziselwa ukuchaza ukukhiqizwa kwezidakamizwa zamaqanda amaningi ukuze kusetshenziswe kwezobuchwepheshe bokuzala ezithandwayo ezifana ne- vitro fertilization (IVF ).
Ngokuvamile, owesifazane ovulates iqanda elilodwa nje umjikelezo ngamunye. Ngokusetshenziswa kwezidakamizwa zokuzala, angakwazi ukukhiqiza amaqanda amaningana, angabuyiselwa kuma-ovari ngaphambi kokuvuna.
Ukuqothulwa kwemvelo akufanele kudidaniswe nokufakwa kwe-ovulation . I-Clomid imithi ejwayelekile yokusebenzisa i-ovulation induction.
Ngesikhathi sokuguqulwa kwe-ovulation, umgomo wama-ovari ukuvuthwa amaqanda owodwa noma amabili kuphela. Nge-superovulation, kuyadingeka amaqanda angaphezu kwamabili.
Ukuvuthwa kwempi kunesinye isikhathi kusetshenziselwa ukwelashwa kwe-IUI . Kodwa-ke, ngenxa yobungozi bokukhulelwa okuphindaphindiwe, ukwelashwa kwe-IUI ngokuvamile kuhilela ukungena kwe-ovulation.
Izingozi zokudlula phezulu zihlanganisa i- ovarian hyperstimulation syndrome , i-torment ovarian , kanye nama- multiple (amawele, ama-triples, njll) ukukhulelwa .
Kukhona izingozi ezingase zibe khona kanye nemiphumela emibi ehlobene nhlobo uhlobo lwezokwelapha ezisetshenziswayo (IVF noma i-IUI), kanye nezingozi ezidakamizwa zokuzala ezikhethiwe. (Okuningi ngalokhu ngezansi.)
Izidakamizwa Zokwelapha Zisetshenziswa
Kukhona imigomo emibili uma kuziwa ekukhunjweni okukhulu:
- Hlanganisa ama-ovari ekukhuliseni amaqanda amaningi
- Vimbela ama-ovari ukukhipha lawo maqanda ngaphambi kwesikhathi
Uma amaqanda egoqa ngokwabo, azolahleka emgodini wesisu. Ku-IVF, udokotela wakho udinga ukwazi ukuwathola ngokuqondile kuma-ovari. Ovulating ngaphambi kokubuyiswa kwamaqanda kungaholela ekujikelezeni kwakho kwe-IVF.
Ukuze kukhuthazwe ukuguqulwa kwemithi, izidakamizwa zokuzala ezijova ezibizwa ngokuthi i-gonadotropin zisetshenziswa:
Ukuvimbela i-ovulation ngaphambi kwesikhathi, noma i-GnRH agonist noma i-GnRH imelene nayo isetshenziswa:
- Imiphumela emibi ye-GnRH Agonists (i-Lupron, i-Synarel, i-Suprecur, ne-Zoladex)
- Ama-Antagonists e-GnRH (i-Antagon, Ganirelix, i-Orgalutran, ne-Cetrotide) Imiphumela emibi
Ingabe i-Clomid noma i-Letrozole isebenzisiwe?
I-Clomid ne- letrozole azivame ukusetshenziselwa ukuphakama okukhulu. Lezi zidakamizwa zokuzala zikhethwa ngokujwayelekile ekufakweni kwe-ovulation. (Uma ufuna nje amaqanda owodwa noma amabili kakhulu.)
Yize kungenzeka ukuthi ube nomjikelezo we-IVF usebenzisa i-Clomid noma i-letrozole, kuzobe kufana kakhulu nalokho okubizwa ngokuthi "umjikelezo wemvelo."
Umjikelezo wemvelo we-IVF wukuthi i-IVF yenziwa ngaphandle kokuqhathaniswa kwama-ovari. Amaqanda owodwa noma amabili atholakala.
Amazinga okubeletha aphilayo aphansi nemigqa yemvelo ye-IVF, nakuba kunezikhathi lapho kungcono ukhetho lwezokwelapha.
Zingaki Amaqanda Ayinjongo?
Inani lamaqanda ofuna ukuvuthwa lizoxhomekeka ekucutshungweni kanye nokwelapha.
Inombolo ethi "ekahle" yamaqanda okubuyiselwayo nayo iyoxhomeka embonweni wakho wezobuchwepheshe kanye nesipiliyoni. Ungesabi ukubuza.
Ngesikhathi sokuqapha kwe-ultrasound yomjikelezo we-IVF, udokotela wakho uzokala futhi abale ukuthi zingaki izinhlobo ze-follicle ezikhulayo kuma-ovari.
Ngaphakathi kwe-follicles kukhona ama-oocyte , noma amaqanda.
Kodwa akuzona zonke izintambo ezizokunika iqanda. Akuzona zonke amaqanda azoba umbungu. Futhi akuwona wonke ama-embryo azoba nenhliziyo enempilo futhi enempilo ngokwanele ukuba adluliselwe.
Isibonelo, ungase ube nezintambo ezingu-10 kodwa uthole amaqanda angu-7 noma angu-8 kuphela. Kusukela kulawo maqanda ayisikhombisa noma ayisishiyagalolunye, kuphela amane noma ayisithupha kuphela angafaka umquba, futhi kuphela amabili noma abathathu kuphela abangaba nempilo enhle yokwedluliselwa.
Yingakho ufuna ukukhiqiza amaqanda amaningana, ukwandisa izinkinga zakho zokukhulelwa.
Ngokuvamile, ngomjikelezo ovamile we-IVF, udokotela wakho uthemba ukuthola okungenani amaqanda ayi-10 avela kumaqanda akho. Noma kuphi phakathi kwamaqanda angu-8 no-15 angabhekwa njengenombolo enhle.
Uma ukhiqiza follicles ezine noma ezimbalwa, udokotela wakho angakwazi ukukhansela umjikelezo we-IVF.
(Isizathu ukuthi izinkinga zakho zokuphumelela ukukhulelwa ziphansi ngamaqanda amane noma ambalwa. Bafuna ukugwema ukubeka engozini bese ukwandisa izindleko zakho zezimali, ngenzuzo encane.)
Uma uveza follicles amaningi kakhulu - njengamaphesenti angu-20 - kungenzeka futhi udokotela wakho angakhansela lo mjikelezo. Lokhu kungenxa yokuthi ingozi ye-ovarian hyperstimulation iphezulu.
(Kunezindlela zokunciphisa ingozi bese uqhubeka nomjikelezo, kwezinye izimo.Ngokwesibonelo, bangathola amaqanda kodwa bangenzi ukuhanjiswa kwembungu. Bangase bafake noma yikuphi imibungu enempilo futhi bahlele ukuwadlulisela emva kokuba ama-ovari akho alulame. udokotela wakho mayelana nesimo sakho esithile.)
Uma une mini noma micro-IVF , umgomo kungenzeka ukukhiqiza follicles ezine noma ezinhlanu kuphela.
Ngenkathi ama-follicle ambalwa kunama-IVF aphelele angabhekwa njengesibonakaliso esibi, phakathi ne-mini-IVF, lokhu kungaba kuhle.
Uma unomjikelezo we-IUI ngokukhulula, akukho okungaphezu kwezine okungcono kakhulu. (Khumbula, uma ugoqa amaqanda amane, kungenzeka ukuthi ungakwazi ukukhulelwa ama-quadruplets.) Odokotela abaningi bahlose amaqanda owodwa noma amabili kuphela umjikelezo we-IUI.
Yiziphi Izinzuzo Zempumelelo?
Amanani okuphumelela ayoxhomekeka kunjani uhlobo lwezokwelapha ezisetshenziswayo (IVF, i-IUI, i-mini-IVF), ukuxilongwa kwakho, kanye nobudala bakho.
Ngokujwayelekile, amazinga e-IVF impumelelo angcono kunezinga le-IUI. Kodwa ngeke ufune ukusebenzisa ukwelashwa okunamandla, okubiza kakhulu kokuzala uma ungadingeki. Kulabo besifazane abangaphezu kweminyaka engama-40 nabesifazane abathola ukuthi bane-primary ovarian insufficiency (eyaziwa nangokuthi i-POI noma ukuhluleka kwe-ovarian ngaphambi kwesikhathi), ukukhululeka kungase kungaphumeleli.
Lokhu akusho ukuthi i-IVF ayikwazi ukukusiza ukuba ukhulelwe. Ungadinga udokotela onolwazi kulezi zimo. Noma, kungase kudingeke ucabange ukusebenzisa i-egg donor . Izinga lokuphumelela le-IVF elinamaqanda amaqanda lihle ngempela. Okufanelekile, udokotela wakho ngeke afune ukukufaka nge-IVF noma ukuphakama okukhulu uma bengacabangi ukuthi kuzokusebenzela. Yingakho ukuhlolwa kokuhlolwa kwe-ovarian kwenziwa.
Ukuhlolwa kwe-Ovarian reserve kuhloswe ukubikezela ukuthi ngubani ongaphenduli kanye nemithi yokuzala ngesikhathi se-IVF. Olunye uhlolo odokotela abathile abakwenzayo ukubikezela ukuthi impumelelo engcono kakhulu yokuzikhukhumeza iyaziwa ngokuthi yinselelo yeComomid.
Umthombo:
Ukukhuthazwa kwe-Ovarian ye-IVF kulabo abaphendula abaphansi. Amasevisi Okukhula Okukhudlwana aseChicago. https://www.advancedfertility.com/ivf-low-response.htm