Uma Kungumqondo Omuhle Nalokho Ongakuveza
Isizathu esivame kakhulu sokukhulelwa kwesisu kukhona uhlobo olungajwayelekile lwe- chromosome olwenza ukuthi ukukhulelwa kungabi namandla. Lokho kuyabangela ukwesaba, kodwa empeleni, emibhangqwaneni eminingi eye yabhekana nobuhlungu bokulahlekelwa okunjalo izimpikiswano ziphezulu zizoqhubeka zikhulelwe futhi ekugcineni zibe nomntwana onempilo. Ngenxa yalesi sizathu, odokotela ngokuvamile abacebisi ukuhlolwa okulandelayo ukuzama ukuthola imbangela yokukhulelwa kwesisu sokuqala, nakuba abanye abazali abanethemba bangase babe nomuzwa wokuthi ukuhlolwa kuzobasiza ukuba bathole ukuvalwa.
Ukuhlolwa kwe-Chromosome kungase kusetshenziswe kakhulu emva kokuhlukunyezwa okuningi. Ukuze ukwenze, isampula yamathambo kusuka kokukhulelwa kwesisu kufanele iqoqwe futhi ihlaziywe ebhodini. Inselelo, ikakhulukazi emva kokukhulelwa kwesisu, kungabe kunzima ukuthola isampuli esanele ngaphandle kokuba owesifazane ehlanjululwe futhi ahlanzwe (i-D & C) -Inqubo ehilela ukukhipha noma yisiphi isisindo esingadluli ngesikhathi sokukhulelwa kwesisu. Uma owesifazane eqala ukuphuma ekhulelwe futhi eqiniseka ukuthi unesisu, udokotela wakhe noma umbelethisi angamtshela indlela yokusindisa izicubu ukuze zihlolwe.
Yikuphi ukuhlola kwe-Chromosome Kungabonakalisa
Ngokususelwa kwinani lama-chromosomes nesakhiwo sabo, ukuhlolwa kwe-chromosome kungagcina noma kukhishwe ukungalingani okusobala njengesizathu sokukhulelwa kwesisu. Isizathu esivame kakhulu se-chromosomal sokukhulelwa kwesisu yi-trisomy. Ezinye zihlanganisa i- triploidy , i-monosomy, i-tetraploidy, noma izinkinga ezihlelekile ezifana nokudluliselwa kwezinto-konke okuvame ukubangelwa ukungafani okuncane kwendoda noma iqanda, kunokuba izuzwe umzali.
Ngesinye isikhathi imiphumela ebonisa ama-chromosomes avamile emntwaneni ongenakulinganiswa izobhekwa kuphela uma umntwana engumfana. Ngenxa yokuthi ngaphezu kwengxenye yemiphumela evamile ye-chromosomally evela ekutheni imithwalo yokukhubazeka ijwayele ukuba yintombazane, abacwaningi bakholelwa ukuthi kuvamile ukuthi izicubu zomama zingcolise imiphumela (nakuba amasu amathebhu aqaphele anganciphisa ukuthi lokhu kwenzeka kanjani).
Ngezizathu zamanani nezindleko, akunakwenzeka ukunquma ukuthi imiphumela yokuhlolwa ivela kumama noma kusuka kumntwana kulezi zimo.
Ukuhlela Ukukhulelwa Kwesikhathi Esizayo
Kungakhathaliseki imiphumela, uma unesidingo se-chromosome ngemuva kokukhulelwa kwesisu ungase ube nemibuzo mayelana nendlela yokuhlela ukukhulelwa esikhathini esizayo. Udokotela osekela noma umeluleki wezakhi zofuzo kufanele akwazi ukuphendula imibuzo yakho. Futhi uma imiphumela yakho yokuhlolwa yembula ukukhulelwa okuvamile kwe-chromosomally noma ayengavumelani, futhi ungaqhubeka nokulahlekelwa okuningi, ungase ufise ukubona ochwepheshe ongakuvivinya ngokunye okubangelwa ukukhulelwa kwesisu.
Uma imiphumela yokuhlola kwakho kwe-chromosome yembula ukuthi kwakukhona ukungavamile, izinkinga ziphakeme kakhulu ukuthi kwakuyinkinga eyodwa yesikhathi esisodwa. Lokhu akusho ukuthi unengozi eyengeziwe yokuba nosana oleso simo esingavamile esikhathini esizayo. Iningi le-chromosome engavamile liwumphumela wamaphutha ekuhlukaneni kweseli se-sperm noma iqanda, futhi isikhathi esiningi ngeke babuyele esikhathini esizayo sokukhulelwa. Ngaphandle kwalesi simiso ukuthi uma imiphumela ibonisa ukuthi umntwana wayene-translocation engalingani, lapho kwenzeka odokotela bangase batusa wena nomlingani wakho ukuba uhlolwe isimo esibizwa ngokuthi i-translocation elinganisiwe.
Emibhangqwaneni ehlangabezana nokukhubazeka okungajwayelekile nokuhlolwa kwembula ukuthi lokhu kwenzeka ngenxa yezinto ezingavamile ze-chromosome, kunezindlela zokuzama ukukhulelwa isikhathi esigcwele nengane enempilo. Enye yalezi zinqubo eyaziwa ngokuthi i- pre-implantation genetic diagnosis , kanye ne- in-vitro fertilization (IVF) . Kuyabiza futhi kaningi kungahlanganiswa nomshuwalense, kodwa ngokuqinisekile kuwufanelekile emibhangqwaneni efisa kakhulu ukuba nezingane eziphilayo.