Ukubheka Ngokucophelela Le ngqungquthela ephikisanayo
Kungenzeka ukuthi uke wazizwa nge-progesterone, ikakhulukazi uma uye wahlaselwa isisu. I-progesterone i-hormone ehlobene nokukhulelwa kanye nomjikelezo wokuya esikhathini.
Izinga le-progesterone likhuphuka inyanga zonke emva kwe-ovulation, lilungiselela ukwelulwa kwesibeletho sokukhulelwa. Emjikelezweni wesisu ongenawo okhulelwe, amazinga e-progesterone akhuphuka ngemva kokuvuthwa nokuwa ngaphambi kokuba owesifazane afike esikhathini sokuya esikhathini. Uma ukhulelwe kwenzeka, izinga leprogesterone kufanele lihlale liphakeme. Ama-ovaries akhiqiza iningi le-progesterone ngokusebenzisa iningi le-trimester yokuqala, kodwa ekugcineni, i-placenta ithatha ukukhiqizwa kwe-hormone cishe ngesonto leshumi lokukhulelwa.
Ngenxa yokuthi i-progesterone idlala indima ekulondolozeni i-uterine lining, abanye abacwaningi bathi i-progesterone encane ngaphambi kokuphuma kwesisu kungase kube nomthelela ekwenzeni ukukhulelwa kwesisu . Kodwa kungakhathaliseki ukuthi ukwengeza i-progesterone empeleni kuvimbela ukuphuma kwesisu kuyindaba yokuphikisana.
Isimo samanje
Njengamanje, ayikho izinhlangano zezokwelapha ezikhuthaza ukuncoma i-progesterone kwabesifazane abanezinkinga zesigaba se-luteal noma izinsizakalo eziphindaphindiwe, ngaphandle kwabesifazane abasebenzisa ubuchwepheshe bokuzala njengo-IVF.
Azikho izifundo zesayensi ezitholile ubufakazi obucacile bokuthi izithako ze-progesterone zivimbela ukukhulelwa kwesisu kwabesifazane abangasebenzisi izindlela zokukhiqiza ezenzakalelayo. Ucwaningo oluningi alutholi umehluko emazingeni okukhulelwa kwamaphesenti uma kuqhathaniswa nabesifazane abathwala izithako ze-progesterone kubantu besifazane ababengenalo.
Ucwaningo oluthile luye lwathola ubufakazi bokuthi ukuthatha izithako ze-progesterone kungase kuzuze abesifazane abaye bahlaselwa isisu, kodwa okwamanje izinombolo zincane kakhulu ukuthi zingasho ukuthi ngabe lokho okutholakele kubalulekile noma cha. Ucwaningo olwengeziwe luzodingeka lwenzeke ngaphambi kokuba ochwepheshe bazi ukuthi ama-supplement ayasiza yini.
Yikuphi konke okushiwo ngendaba?
I-progesterone ephansi ekukhulelweni ihlotshaniswa nakanjani nokukhulelwa kwesisu, kodwa isizathu sokuphikisana. Ngakolunye uhlangothi, amazinga aphansi kakhulu angase abangele ukuphuma kwesisu uma isisu singakulungeli ukusekela ukukhulelwa, mhlawumbe ngenxa yokuthi ama-ovari anezinkinga zokukhiqiza i-progesterone eyanele ngesizathu esithile.
Ngakolunye uhlangothi, odokotela abaningi bakholelwa ukuthi i-progesterone encane nje isho ukuthi isisu esisodwa siseduze kwezinye izizathu. Ngalolu caba lokucabanga, amazinga aphansi ayisigqila sokuqala sokuthi umzimba ulungele ukukhukhumeza ukukhulelwa okwehlulekile kakade kwezinye izizathu, njengokungavamile kwe-chromosomal emntwaneni osathuthuka, futhi ukuxhaswa kwe-progesterone akusizi ngalutho.
Okwamanje, akekho owazi impendulo efanele, futhi isihloko siba yindaba yokuphikisana okuhle.
Izinzuzo
Odokotela ngabanye bangase babe nokuhlangenwe nakho kwempilo lapho besifazane bebona ukuthi abesifazane banesisu esiphuthumayo bese sebekhulelwa ngokuphumelelayo emva kokuxhaswa kwe-progesterone, ngakho-ke bangaba ngamakholwa aqinile kulo mqondo wokuthi empeleni usebenza.
Abanye odokotela basebenzisa izithako ze-progesterone kuphela kwabesifazane abaye bahlola kakade njengokuba ne-progesterone encane. Odokotela abasebenzisa le ndlela bangase babe nomuzwa wokuthi izifundo ezikhona azizange zihlole iziguli ngokufanele, njengoba izifundo eziningi ze-progesterone okwamanje azihlukanisi abesifazane nabamazinga aphansi e-progesterone avela kwabesifazane abaye babhekana nokuhlukunyezwa kwezinye izizathu . Futhi, bangase babe nokuhlangenwe nakho kwempilo lapho bebona abesifazane abanezinga eliphansi le-progesterone bephela bephethe umntwana isikhathi emva kokuxhaswa, ngakho bakholelwa ukuthi kusebenza.
Njengoba kunikezwa ukuthi umzimba uveza i-progesterone ngesikhathi sokukhulelwa noma kunjalo, futhi eziningi ezithengiswayo emakethe zine-makeupone efana neprogesterone eyenziwa emzimbeni, odokotela abaningi banomuzwa wokuthi ukuxhaswa kwabesifazane abanamazinga aphansi akunakwenzeka ukulimaza ngisho noma akusizi. Bakhetha ukuhamba nefilosofi ukuthi uma i-progesterone ingakwazi ukulimaza futhi ingasiza, ingase ibhale futhi.
I-Cons
Odokotela abangaqapheli izithako ze-progesterone bangase bazizwe benqikaza ukunikeza noma imuphi umuthi ngaphandle kwesibonakaliso esicacile sokuthi kusebenza-futhi banomhlabathi omuhle womlando wokuma. Ema-1950s ukuya ngawo-1970, odokotela babeka umuthi okuthiwa i-DES kubantu besifazane abakhulelwe benomqondo wokuthi uzovimbela ukukhulelwa kwesisu-lesi sidakamizwa kamuva sabangela ukungavamile kokuzala okunganeni.
Nakuba odokotela abaningi bezwa izithako ze-progesterone cishe ziphephile, akunakwenzeka ukusho ukuthi eminyakeni eyi-10 noma engu-20 isifundo singase sibone izingozi zokusebenzisa ukwesekwa kwe-progesterone yokufakelwa ngesikhathi sokukhulelwa. Odokotela bangalinda iziqondiso ezicacile ngaphambi kokuqhubeka.
Odokotela bangase babe nomuzwa wokuthi, kuze kube yilapho ubufakazi besayensi bubonisa inzuzo ecacile, cishe kungenzeka ukuthi i-progesterone encane nje isho ukuthi isisu siphumelele, futhi lokho okuchaza ukuthi i-progesterone uma ukukhulelwa sekuvele kuhloswe ukukhulelwa kunganciphisa ukuphuma kwegazi.
Ekuxoxiseni ubufakazi obungakahleleki lapho i-progesterone ibonakala isebenza khona, odokotela abenqaba izithako ze-progesterone bangase bakhombise umqondo wokuthi abesifazane abanokukhubazeka okuphindaphindiwe bavame ukuba nempumelelo ephakeme ngisho nangaphandle kokwelashwa-ngakho-ke, ngokungalawuliwe okungalawulwayo, kungenzeka owesifazane ongezelelwe nge-progesterone wayeyokwazi ukukhulelwa ngokuphumelelayo ngisho nangaphandle kokwelashwa.
Lapho Uqala khona
Odokotela babe nemibono ehlukile ku-progesterone, ngakho-ke uzothola abanye abayinikezela kuwo wonke owesifazane oye waba nokuphutha kwamaphutha okuphindaphindiwe, abanye abanika kuphela abesifazane abanamazinga aphansi e-progesterone, kanti abanye abangeke basebenzise izithako ze-progesterone (ngaphandle kweziguli besebenzisa izindlela zokwenza izakhi).
Kuyiqiniso ukuthi akekho owaziyo ngempela ukuthi ama-progesterone ayesebenza yini noma cha, nokuthi akukho nhlobo yeprogesterone eyokwenza umehluko emkhakheni wokugcina wabesifazane abanokukhubazeka ngenxa yokungahleleki kwe- chromosomal noma izimbangela ezifanayo.
Izithako ze-progesterone cishe ziphephile. Akekho othole ubufakazi bokuthi bangabangela ukulimala. Uma udokotela wakho ekunxusa ukuthi usebenzise i-progesterone, qiniseka ukuthi uxoxe nganoma yikuphi ukukhathazeka ongase ube nako futhi uthathe izinhlangothi zombili ukuba uziphendule ngaphambi kokwenza isinqumo sakho. Ngokufanayo, uma udokotela wakho engakunikeli ukunikeza i-progesterone, qiniseka ukuthi ucabangisisa ngezizathu zalesi simo ngaphambi kokwenza isinqumo mayelana nokunakekela kwakho esikhathini esizayo.
> Imithombo:
> Ukukhathazeka Ngokuphathelene Nokuthuthukiswa Kwesibalo Sokuqala. I-American Association Ukukhulelwa. http://americanpregnancy.org/pregnancy-complications/early-fetal-velopment/.
> Daya S. Luteal Support: Progestogens for Ukukhulelwa Ukukhulelwa. Maturitas . 2009; 65. doi: 10.1016 / j.maturitas.2009.09.012.
> Haas DM, uRamsey PS. I-Progestogen yokuvimbela ukushada. Database Cochrane Yokuhlolwa Okuhlelekile 2013, Issue 10. Art. Inombolo: CD003511. I-DOI: 10.1002 / 14651858.CD003511.pub3.
> I-Progesterone Supplementation Ngesikhathi seLuteal Phase nasekukhulelweni kokuqala ekuPhilweni kokungafihli: i-Bulletin yezemfundo. Ukuzala nokuhlunga . 2008; 90 (5). i-doi: 10.1016 / j.fertnstert.2008.08.064.
> Wahabi HA, Fayed AA, Esmaeil SA, Al Zeidan RA. I-Progestogen Yokuphatha Ukwesatshalaliswa Kwezisu. Database Cochrane Yokuhlolwa Okuhlelekile 2011, Issue 12. Art. Inombolo: CD005943. I-DOI: 10.1002 / 14651858.CD005943.pub4.