I-folic acid, ngezinye izikhathi ebizwa ngokuthi i-vitamin B-9 noma i-folate, i-vithamini engenawo amanzi emndenini wakwa-B. Wonke umuntu udinga ukudla okufaka i-folic acid, kungakhathaliseki ukuthi bayakhulelwa noma cha, njengoba ukungabi namuntu kungabangela izinkinga ezinkulu zezempilo. Kodwa-ke, ukudla okwanele kwe-folic acid kubhekwa njengokubaluleke kakhulu kwabesifazane abaneminyaka yokubeletha.
Abaningi okwesithathu kwabesifazane baseNyakatho Melika bangase bangatholi i-folic acid eyaneleyo ekudleni kwabo, naphezu kokukhishwa kwemikhiqizo yokusanhlamvu ne-nutrient.
Izinkinga ze-folate ne-Neural Tube
Ukuphikisana okuqine kakhulu kwabesifazane abakhulelwe abadinga ama-folic acid supplements bavela ku-tie phakathi kokudla okunamandla okunciphisa futhi kuncishiswe ingozi yokuba nengane eneziphambeko ze-neural tube . Amaphutha we-Neural tube ayingxenye yokukhubazeka okuzalwa kokuzalwa okuthinta ubuchopho nomgogodla, okuvame kakhulu ukuba yi-spina bifida ne- anencephaly . Amaphutha we-Neural tube angakhubaza kakhulu noma abulale ngisho nengane ekhulayo.
Kukhona umzimba omkhulu wocwaningo obonisa ukuthi omama banesisindo esifanele se-folic acid ngaphambi kokukhulelwa banamaphesenti angu-50 kuya ku-70% engozini encane yokuba nengane eneziphambeko ze-neural tube. I-tube ye-neural ivala ngosuku lwama-28 emva kokukhulelwa, noma eduze kwamasonto amabili emva kwesikhathi sakho esingekho, ngakho-ke ezimweni eziningi, isikhathi esibucayi singase sidlule ngaphambi kokuthi ufunde nokuthi ukhulelwe.
Ngenxa yokuthi ukukhulelwa okuningi akuhlelwe, i-CDC incoma ukuthi abesifazane abaneminyaka yokubeletha baqiniseke ukuthi badla okungenani ama-micrograms angu-400 (mcg) we-folic acid usuku ngalunye-nokuthi labo abahlela ukukhulelwa kufanele baqiniseke ukuthi bathola leyo mali okungenani izinyanga ezintathu ngaphambi kokukhulelwa. Lelizinga lokudla lingatholakala kalula ngokuthatha i-vitamin yokubeletha (noma enye i-multivitamin ene-400 mcg ye-folate), kodwa futhi kungenzeka ukuthola i-folic acid eyanele ekudleni kwakho ngaphandle kokugcwalisa uma uqikelela ukukhetha u- folate- ukudla okucebile .
Uma uye waba nomntwana nge-neural tube defect esikhathini esidlule, udokotela wakho angase anikeze iseluleko sokuthi uthatha ngisho naphezu kuka-400 mcg we-folate ngosuku ngelinye isikhathi ngaphambi kokuba ukhulelwe futhi. Khuluma nodokotela wakho mayelana nalokho okwenzayo ngomqondo wakho.
Ezinye Izinzuzo Ze-Folic Acid
Ngisho noma isikhathi esibucayi seziphambeko ze-neural tube ngaphambi kokuba uthole ukuthi ukhulelwe, lokho akusho ukuthi i-folic acid ayinalutho uma usuvele ukhulelwe. Ihlala isisondlo esibalulekile sokuhlukaniswa kwamaselula nokukhula, okwenzela izizathu zokuyithatha ngesikhathi sokukhulelwa konke okusobala.
Ngaphezu kwalokho, kuye kwaba nobufakazi bokuthi i-folic acid inganciphisa ingozi yokunye ukukhubazeka kokuzalwa kanye nokuthi amamama aphansi e-folic acid angase abe nomngcipheko omkhulu wokukhulelwa kwesisu , ukuphazamiseka kwamapayipi kanye nokuhanjiswa kwangaphambi kwesikhathi- mhlawumbe ngenxa yobuhlobo phakathi kwephansi folic acid namazinga e-homocysteine .
Kodwa Ingabe Akuyona Inhlekelele Eningi kakhulu?
Akukhona umkhawulo ophezulu owaziwayo wokuthi u-folic acid uvikelekile kangakanani, kepha odokotela ngezinye izikhathi banxusa abesifazane ukuthi bahlale bewadla nge-folic acid ngaphansi kwe-1000 mcg ngosuku, ngenxa yemibiko embalwa ukuthi ukuxhaswa kwe-folic acid okungaphezu kwalokho kungase kuhlotshaniswe nokwanda kancane ingozi yokuvuthwa nezinye izinkinga zokuphefumula emntwaneni.
Kukhona ubufakazi obuningi obusezingeni eliphezulu lokusebenzisa ukuxhaswa kwe-folic acid kunokufakaza okuphikisayo, kodwa lokhu okutholakele kubonisa ukuthi ukugcina ngaphakathi kwemingcele ephakanyisiwe kungase kube umbono omuhle.
Imithombo:
UCallaway, Leonie, uPaul B. Colditz noNicholas M. Fisk. "I-Folic Acid Supplementation nokuzalwa kwangaphambi kokuzalwa kwangaphambili: Ukwengeza iGrist kuMill?" I- PLoS Med 2009 Meyi; 6 (5): e1000077.
Amaqiniso Nge-Folic Acid. I-CDC. http://www.cdc.gov/ncbddd/folicacid/about.html
Håberg, SE, SJ London, H Stigum, P Nafstad naseW Nystad. "Izithako ze-folic acid ekukhulelweni nasekuqaleni kwengane yokuphefumula." Archives of Disease In Childhood 2009; 94: 180-184.
Scholl, Theresa O. noWilliam G Johnson. "Folic acid: ithonya emphumela wokukhulelwa." I-Am J Clin Nutr. 2000; 71 (suppl): 1295S-303S.
USherwood, Kelly L, uLa. A. Houghton, uValerie Tarasuk noDeborah L. O'Connor. "Ingxenye Eyesithathu Yomama Abakhulelwe Neziphikisanayo Kungase Kungabikho Ukuhlangana Nezintatheli Zabo Okudingekayo Ekudleni Kodwa Kusekelwe Ezilinganisweni Ezigunyaziwe zeFolic Acid Fortification." J. Nutritional. 2006 136: 2820-2826.