Izimpendulo Zama-Clomid Doping Izinsolo
Njalo njalo, indaba iphula ezindabeni mayelana nomdlali ohluleka ukuhlolwa kwezidakamizwa ngenxa yokusetshenziswa kwe- Clomid . Umdlali weBhola uRobert Mathis we-Columbus yase-Indianapolis usolwa ngokudlwengula nge-clomiphene futhi wamiswa okwesikhashana ukudlala i-NFL. UMatis wabika ukuthi uthatha uComomid njengendlela yokwelashwa kwabesilisa. U-Sprinter uJason Livermore kanye no-baller net Simone Forbes bangabanye abagijimi abaye bahlola ukuthi bayasebenzisa i-Clomid ngesikhathi sokuhlolwa kwezidakamizwa zezemidlalo.
I-Clomid, eyaziwa nangokuthi i-clomiphene citrate, ivame kakhulu ukuthi iyisidakamizwa sokuzala, kodwa ingasetshenziswa nabathile ngezinhloso ezijabulisayo. I-Clomid ibhalwe njengento evinjelwe yi-NFL, iKomidi Lomhlaba Wonke Wama-Olympic, ne-World Anti-Doping Agency. Uma ukusetshenziswa kwe-Clomid kutholakala ekuhlolweni okungahleliwe kwezidakamizwa, umgijimi angahle ahlawulwe.
Kungani umgijimi angathatha umuthi wokuzala njengoClomid?
Abanye abagijimi babanjwe bethatha isimangalo sikaClomid ukuthi besithatha ukuphatha ukungabi namuntu okungenalutho . Bathi bazama nje ukuba nengane. Kungabe kuyiqiniso yini ukuthi indoda ingathatha i-Clomid ukuze ilawule ukungabi namuntu? Ingabe i-Clomid ayiyona imithi yokuzala yowesifazane?
Indlela abagijimi abangasebenzisa ngayo i-Clomid yokuthuthukisa ukusebenza noma ukukhishwa kwe-Cover-up
Ngaphambi kokuba sikhulume nge-Clomid, kudingeka sikhulume kafushane nge-androgens (njenge-testosterone) ne-estrogens.
I-Androgens ivame ukucatshangwa ngokuthi ama-hormone "abesilisa" nama-estrogen njengamahomoni "abesifazane".
Nokho, zombili izinhlobo zamahomoni zikhiqizwa kokubili. Amadoda ngokwemvelo anamazinga aphezulu ama-androgens namazinga aphansi ama-estrogen, futhi abesifazane banamazinga aphezulu ama-estrogens namazinga aphansi a-androgens.
I-Testosterone, enye ye-hormone ye-androgen eyinhloko, idlala indima enkulu ekuthuthukiseni ubukhulu bemisipha namandla.
Kuphinde kuthinte ukushayela ucansi, amazinga omzimba kanye namandla, nokukhula kwezinwele zesilisa (njengezinwele zesifuba nesifuba).
Kanye nokuzivocavoca nokudla okunempilo, amadoda anamazinga e-testosterone asezingeni eliphakeme azoba nesisindo esiningi kakhulu sokwakha imisipha namandla.
Abagijimi bangase bazame ukukhulisa ukusebenza ngokuthatha ngokungemthetho u-testosterone wokufakelwa, ngokuvamile ngesimo sephilisi, noma ama-hormone e-testosterone yemvelo, ngokuvamile nge-injection. Ngokwesibonelo, i-anabolic steroids, ifomu le-testosterone.
Ngaphandle kokuyingozi futhi engozini, ukuthatha ama-androgens engeziwe kubhekwe ukukopela endaweni yezemidlalo. Izinhlangano eziningi zezemidlalo nezokuqeda ukuvimbela ukusetshenziswa kwezidakamizwa namahomoni ase-androgen.
Abagijimi badinga ukuthatha izivivinyo ezingavumelekile, ezingahleliwe ezifuna ubufakazi be-androgen doping. Ngisho nezinyanga emva kokuthatha i-androgens yokwenziwa, i-trace amounts iyabonakala ekuhlolweni kwegazi.
Ukuze abagijimi bafuna ukuthuthukisa ukusebenza, ubufakazi obuhlala isikhathi eside obushiyelwe ukusetshenziswa kwe-androgen engafanele kwenza kube yinto engozini.
Bambalwa abagijimi abahlakaniphile bangazama ukuzama.
Nokho, ukuthatha u-testosterone ngokuqondile kuyindlela eyodwa yokuthuthukisa ama-androgen amazinga. Kungenzeka futhi ukuthuthukisa i-testosterone ngokungaqondile.
Yilokho okushiwo i-Clomid.
Khumbula kuqala ukuthi amadoda ane-estrogen ne-estrogen receptors, engaphansi kwabesifazane abanakho.
I-Clomid isebenza ngokuvimbela ama-estrogen receptors emzimbeni. Ngenxa yokuthi ama-estrogen receptors avinjiwe, i-estrogen ejikelezayo emzimbeni ayitholakali ngokuvamile.
Lokhu kuholela ekutheni ama-hormone okhiqiza ama-hormone acabange amazinga e-estrogen aphansi (ngisho noma engekho), ngakho-ke ama-gland azama ukukhiqiza ama-estrogen amaningi. Umzimba wenza lokhu ngokukhulisa ukukhiqizwa kwamanye amahomoni amabili abalulekile okuzala: i-LH ne-FSH.
Lokhu kusho ukuthini ngo-testosterone? I-testosterone ikhiqizwa ngamaseli awaziwa ngokuthi amangqamuzana e-Leydig. Baveza testosterone ngokuphendula i-LH. Amazinga aphakeme kakhulu e-LH asho amazinga aphezulu e-testosterone.
Yilapho i-Clomid iphakamisa amazinga e-testosterone ngokungaqondile. Umdlali akayithathi ngokuqondile ukuthatha u-testosterone owengeziwe, kodwa ekhohlisa umzimba wakhe ekukhiqizeni okuningi ngokwakho.
I-Clomid akuyona kuphela imithi engasetshenziswa ngale ndlela. Ezinye zihlanganisa i-chlorotrianisene (TACE), ethamoxytriphetol (MER-25), ne-tamoxifen (i-Nolvadex). Eziningi zalezi zidakamizwa zivinjelwe yi-ejenti yokudotshwa.
I-Clomid ingathathwa ngumdlali ofuna ukukhulisa ukusebenza ngokukhulisa ngokungaqondile amazinga e-testosterone emvelo emzimbeni, kodwa ingasetshenziswa futhi ukulwa nemiphumela emibi ye-anabolic steroid ukusetshenziswa.
Ngokusebenzisa i-anabolic steroid, umzimba ugcina ekunciphiseni noma ukuyeka ukukhiqiza u-testosterone ngokwakho. Amazinga aphansi e-testosterone angabangela izinkinga ezinkulu zempilo. I-Clomid ingasiza umzimba ukuqala kabusha ukukhiqizwa kwaleli hormone ebalulekile.
Ingabe Amadoda Athatha I-Clomid Yokungafaki? Akuyona I-Clomid Yowesifazane Okwamanje?
I-Clomid ingasetshenziselwa ukuphatha ukungasebenzi komuntu kwezinye izimo. Yize ikakhulukazi isetshenziselwa ukwelapha izinkinga zokuvuthwa kwabesifazane, ochwepheshe bokuzala bayayinika amadoda futhi.
Njengoba ufunda ngenhla, i-Clomid ingasiza ekukhuliseni amazinga we-testosterone. Esinye isizathu esingaba sempilo embi ye-semen kanye nokubala okuphansi kwe-sperm kungaba yi-testosterone ephansi, futhi i-Clomid ingakwazi ukuxazulula lokhu ezimweni ezithile.
Noma nini lapho i-Clomid ne-doping ithola izindaba, izitolo zemidiya zithanda ukukhomba ukuthi i-Clomid ayinayo imvume ye-FDA yokuphathwa kokwelashwa kwamadoda.
Futhi lokhu kuyiqiniso. Ukusebenzisa i-Clomid ukuphatha ukungabikho komuntu kubhekwa njengento engekho-ukusetshenziswa kwelebula. Noma kunjalo, lokhu akuyona into yokuthola konke okujabulisayo. Kokubili imithi ejwayelekile kanye nokuzala, ukusetshenziswa kwelebuli-yezidakamizwa ezihlukahlukene-akuyona into engavamile.
Kwabesifazane, isibonelo, i- metformin ingasetshenziselwa ukwelashwa kokuphumula okungajwayelekile noma ukuvota okungavamile, ikakhulukazi kwabesifazane abane- PCOS . Kodwa i-metformin yisidakamizwa sikashukela kanti hhayi i-FDA evunyelwe njengomuthi wokuzala.
I-Lupron ingenye isidakamizwa esingavunyelwe yi-FDA njengomuthi wokuzala, kodwa isetshenziswa ngesikhathi sokuphathwa kwe- IVF .
Yini Abadlali Abaqeqeshiwe Abafisa Ukuthi Benzeni Uma Badinga Ukwelapha Kwabantu Abesilisa?
Abagijimi kufanele bahlole inhlangano yezemidlalo abayidlalayo ngaphambi kokuqala noma yimiphi imithi ohlwini olungavunyelwe. Kungenzeka kube khona okunye okwenziwe. Izinkinga ziqala lapho abadlali behluleka ukudalula iziphathimandla ezifanele izidingo zabo zezokwelapha.
Uma umgijimi kudingeka athathe i-Clomid ngezizathu zezokwelapha, angafaka isicelo sokuthi yini eyaziwa njenge-Treatment Use Exemption (TUE). Lokhu kuzovumela umgijimi ukuba asebenzise imithi ngokuvamile evinjelwe isikhathi esithile esithile.
Kubalulekile ukufaka isicelo salokhu kwemvume ngisho noma ngabe uzothatha nje isidakamizwa isikhathi esifushane. Isidakamizwa nemiphumela yaso ingahlala isikhathi eside ohlelweni lwakho. Ukudlala kuphephile futhi usebenzise isicelo sokukhululwa, kungakhathaliseki ukuthi imithi ephikisiwe oyisebenzisayo nokuthi uzokwelashwa isikhathi eside (noma esifushane).
Kubalulekile futhi ukuveza ukuthi i-Clomid ayiyona indlela evame kakhulu noma ephumelele kakhulu ekwelapheni ukungasebenzi komuntu.
Isibonelo, kuvame kakhulu ukuthi amadoda abe nezibalo ezingavamile zesidoda namazinga avamile e-testosterone. Eziningi zalezi zimo, imbangela yezibalo ezingavamile zesidume aziwa.
Kubantu abahlangabezana nezibalo ezingavamile zezidakamizwa ngenxa yezizathu ezingaziwa, ucwaningo alutholanga i-Clomid ukuba imithi ewusizo.
I-Clomid ingaba nokuthuthukisa ukusebenza kwezemidlalo kwabesifazane?
Bobabili abadlali besifazane nabesilisa bangasebenzisa kabi izidakamizwa ukuthuthukisa ukusebenza, kodwa nokho, asikaze sizwe ngamathimpi abesifazane abanjwe bebamba uComomid.
(Yebo, ngiyaqaphela ukuthi imidlalo eyenza izihloko eziphathelene nokudambisa izidakamizwa ngokuvamile ilawulwa yindoda, kodwa ama-Olimpiki, isibonelo, afaka bobabili abashadile endaweni yokuncintisana kakhulu.)
Lo mbuzo obalulekile ngoba abagijimi besifazane - ngenxa yamakhomithi abo aphansi kakhulu - basengozini yokuthola ukuvota okungekho emthethweni noma engekho. Akuyona into engavamile kubagijimi besifazane ukuba bayeke ukuthola isikhathi sabo noma babe nokukhanya okuncane kakhulu, okuya esikhathini . Yilokho kanye ukuthi i-Clomid isho ukuthini ukuphatha.
Nazi izindaba ezinhle: ucwaningo lwamanje luye lwabona ukuthi i-Clomid ayikhulisi amazinga wegazi we-testosterone kubesifazane. Ngakho-ke, i-Clomid akufanele ithathwe njengento yokudonswa kwabadlali besifazane.
Noma kunjalo, kufanele uhlole njalo ubudlelwane bakho bezemidlalo ngaphambi kokuqala noma yikuphi ukwelashwa.
Ngezinye izikhathi i-Clomid ifihlekile kumikhiqizo yokusebenza ye-Blackmarket
Ama-Bodybuilders nabagijimi bangase bathambekele ekuthengeni imikhiqizo ku-intanethi emenyezelwe ukuthuthukisa ukusebenza. Eminye yale mikhiqizo ingahle ifakwe njengokuthi iqukethe "zonke izithako zemvelo" noma isimanga ukuthi ayikho into evinjelwe ngokuqondile.
Kodwa-ke, kwenzeka ukuthi ezinye zalezi mikhiqizo ye-blackmarket zaziqukethe i-citrate yamagama engakaziwa.
Omunye kufanele ahlale eqaphe lapho ethenga izithako noma izidakamizwa ku-inthanethi ezivela emithonjeni engabaza. Ngeshwa, ukungazi ukuthi umkhiqizo owuthathe uqukethe into evinjelwe ngeke ikukhiphe inkinga.
Izwi elivela ku-Verywell
Bonke abagijimi-abesilisa nabesilisa-banesibopho sezidakamizwa namahomoni abathathayo, futhi kufanele bazi ukuthi imiphi imishanguzo ohlwini lwamatshe alinqatshelwe.
Ikakhulukazi uma usebenza nama-hormone, kufanele uqinisekise kokubili udokotela wakho nezinhlangano ezifanele zokugijima ukuthi ukwelashwa kwakho ngeke kuholele ekuhlawuleni izinsolo noma izinsolo zokudlwengula.
Njengoba abanye abagijimi baye bathola ubuhlungu, ukungabi nemithetho imithetho akusilo isizathu.
Imithombo:
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I-Handelsman DJ. "Ukuqothulwa kwe-androgen engaqondile ngokuvimbela i-estrogen ezemidlalo." I-Br J Pharmacol. 2008 Jun; 154 (3): 598-605. i-doi: 10.1038 / bjp.2008.150. Epub 2008 Apr 21. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2439522/
I-Handelsman DJ. "Ukubuyekezwa komtholampilo: Isizathu sokuvimbela i-gonadotropin yabantu be-chorionic kanye nabavimbeli be-estrogen emidlalweni." I-Clinic ye-Clin Endocrinol. 2006 Meyi; 91 (5): 1646-53. Epub 2006 Feb 14. http://www.ncbi.nlm.nih.gov/pubmed/16478815
U-Whitten SJ1, Nangia AK, uKolettis PN. "Khetha iziguli ezine-hypogonadotropic hypogonadism zingaphendula ukwelashwa nge-clomiphene citrate." UFertil Steril. 2006 Dec; 86 (6): 1664-8. Epub 2006 Sep 27.