Ukuqonda i-Polycystic i-Ovarian Syndrome Izimpawu, Ukuxilongwa, Nokunakekelwa
I-Polycystic ovarian syndrome, noma i-PCOS , iyisifo se-endocrine kanye nesisusa esijwayelekile sokungabikho kwabesifazane. Ku-PCOS, ama-hormone asithinta uhlelo lokuzala aluvamile, okuholela ekuvuthweni okungavamile noma okungekho. I-PCOS iyisifo esivamile, esithinta amaphesenti angu-8 wabesifazane.
Abesifazane abane-PCOS bavame ukuba ne-polycystic ovaries. Lokhu kusho ukuthi ama-ovari anama-cysts amancane, angenabuhlungu futhi angenabuhlungu.
Ngesikhathi sokuhlolwa kwe-ultrasound, ama-cysts amancane angase afane ne-string ye amapharele. Noma kunjalo, ama-ovaries ama-polycystic awasho ngaso sonke isikhathi i-PCOS. Ucwaningo luye lwabona ukuthi abanye besifazane banama-ovarie we-polycystic, i-ovulation evamile, futhi azikho ezinye izibonakaliso zesifo se-endocrine njenge-PCOS.
Ukuthola okuvamile nge-PCOS kungamazinga ajwayelekile angama-hormone a-androgen. Nakuba i-androgens itholakele kokubili amadoda nabesifazane, kubhekwe njengama-hormone abesilisa abakhulu. Amazinga aphezulu e-androgen ahlobene nezinye zezimpawu ezibonakalayo ezicindezelayo ze-PCOS, kuhlanganise namacne nokukhula kwezinwele okungavamile.
Yiziphi Izimpawu Ze-Polycystic Ovarian Syndrome?
Izimpawu ze-polycystic ovarian syndrome zingabandakanya:
- ukungabikho
- ukuvuthwa okungavamile noma okungabikho ( ukugcoba )
- i-amenorrhea (ukungabi khona kwemijikelezo yenyanga ukuya esikhathini) noma i-oligomenorhhea (imijikelezo engavamile yenyanga yokuya esikhathini)
- ukukhulelwa kwesisu okuphindaphindiwe
- ukukhula kwezinwele okungavamile, okwaziwa nangokuthi i-hirsutism, etholakala phezulu kwindebe, ingxube, ezungeze izingono, noma esiswini
- i-acne
- ikakhulu isikhumba samafutha nezinwele
- ukulinganisa iphathini lesilisa
- ukukhuluphala
- ukutholakala kwama-ovaries we-polycystic ngesikhathi sokuhlolwa kwe-ultrasound
- insulin ukumelana
- amazinga aphakeme a-androgens, awaziwa nangokuthi hyperandrogenism
- Amazinga aphezulu we-hormone LH (okwenza ukuhlolwa kwe-ovulation ekhaya) kunzima ukuyisebenzisa)
Awudingi ukuthi ube nazo zonke izibonakaliso ezingenhla ukuthi zitholwe nge-PCOS, futhi i-PCOS ayizibonakali ngendlela efanayo kuwo wonke owesifazane.
Isibonelo, abesifazane abaningi abane-PCOS abanalo ukukhula kwezinwele okungavamile futhi basesisindo esinempilo. Abanye besifazane abane-PCOS bangase bangabi nesikhathi sokuya esikhathini izinyanga ngezikhathi, kanti abanye besifazane abane-PCOS bangase babe nemijikelezo encane engavamile.
Ngoba i-PCOS itholakala ngokubheka isithombe esikhulu, futhi ngokungafaki ezinye izifo ezingase zibe nezimbangela ezifanayo, kubalulekile ukubona udokotela wakho ukuze ahlolwe kahle.
I-Polycystic i-Ovarian Syndrome Yenza kanjani ukungabi nalutho?
Amazinga we-hormone engavamile ahlotshaniswa ne-PCOS aholela ezinkingeni ezine-ovulation. Lezi zinhlawulo ekuvuthweni yiyona imbangela enkulu yokungasebenzi.
I-PCOS ihlotshaniswa nengozi ephezulu yokukhulelwa kwesisu. Ukucwaninga nge-PCOS kubonise ukuthi izinga lokukhulelwa kwesisu lingase liphakeme ngamaphesenti angu-20 kuya ku-40, okuphindwe kabili kunani labantu jikelele.
Akucaci ukuthi kungani ukukhulelwa kwesisu kujwayelekile kubantu besifazane abane-PCOS, kodwa ezinye izinkolelo zihlanganisa okulandelayo:
- ikhwalithi yeqanda elimpofu, elihlobene nokuvuthwa kwesikhashana ngaphambi kwesikhathi
- insulin ukumelana
- imvelo encane engcono kakhulu ye-embryo ukuze ifakwe emgqeni wesibeletho (ngenxa yamazinga angamajwayelekile angama-hormone ahlobene ne-PCOS)
Uphi I-Polycystic Ovarian Syndrome Eyatholakala?
Akuwona wonke umuntu ovumelene nemigomo yokuhlola i-PCOS, futhi incazelo yayo ishintshiwe phakathi neminyaka.
Lokho kusho ukuthi indlela ejwayelekile kakhulu yokuxilonga okwamanje isetshenziselwa ukuthi kudingeke ukuthi kusetshenziswe okubili kokunye kokulandelayo okulandelayo:
- imijikelezo engavamile noma engekho yokuya esikhathini, okubangelwa ukugcoba okungapheli
- kungaba ukuqinisekiswa kwegazi noma izibonakaliso zangaphandle zamazinga aphezulu we-androgens (ukukhula kwezinwele ezingavamile, izigaxa)
- ukutholakala kwama-ovaries we-polycystic, njengoba kuboniswa ukuhlolwa kwe-ultrasound
Ngaphezu kwalokho, ezinye izimbangela zokugcoba noma amazinga aphezulu a-androgen kumele aqedwe. Lokhu kuvame ukuhlanganisa ukuhlolwa kwe-adrenal hyperplasia engavamile, izicubu ze-androgen-secreting, kanye ne-hyperprolactinemia.
Uhlobo Luni Lokuhlolwa Olubandakanya I-Polycystic Ovarian Syndrome?
Umsebenzi wegazi uzoyalelwa ukuba uhlole amazinga e-hormone, amazinga kashukela egazi (for insulin resistance), namazinga e-lipid.
I-ultrasound ehamba phambili ingahle ilandiswe , ukuze ubone ukuthi ama-ovari ayabonakala yini i-polycystic.
Ukuthatha umlando oningiliziwe kuyingxenye ebalulekile yokuxilongwa kwe-PCOS. Udokotela wakho uzofuna ukwazi ukuthi imijikelezo yakho yokuya esikhathini ejwayelekile ikhona, bese ubuza mayelana nokukhula kwezinwele okungadingeki. Ungase ulingeke ukuba ungakhulumi ukukhula kwezinwele okungadingeki ngenxa yokwenza amahloni, kodwa kubalulekile ukuthi utshele udokotela wakho ngale nkinga uma unayo.
Yiziphi Izindlela Zokwelapha I-PCOS?
Ukwelashwa kwe-PCOS kuzoxhomeka noma ngabe uzama ukukhulelwa noma cha. Uma ukukhulelwa akuyona into ephambili, amaphilisi okulawula ukubeletha angalawulwa ukusiza ukulawula imijikelezo yakho kanye nokusiza ukunciphisa izinwele nokukhula okungadingeki kwezinwele.
Abanye besifazane besaba ukuhamba ngamaphilisi okulawula ukubeletha ngoba bacabanga ukuthi kuzolimaza kakhulu ukuzala kwabo. Ucwaningo lokulawulwa kokuzalwa alukatholakali lokhu kuyiqiniso. Ukulawulwa kokuzalwa akumele kungonakalise ukuzala kwakho kwesikhathi eside .
Kodwa-ke, kubalulekile ukwazi ukuthi iphilisi "ayiphilisi" i-PCOS yakho. Ungase uqale ukuthola imijikelezo evamile ngenkathi kuphilisi. Lezi zidalwe ngokwezifiso. Uma usuyeke ukuthatha iphilisi, uma imijikelezo yakho ingavamile ngaphambili, cishe ngeke iphinde ibe yinto engavamile.
Uma une-acne njengengxenye ye-PCOS yakho, kufanele uhambe ubonane nesidermatologist. Amaphilisi okulawula ukubeletha ngezinye izikhathi anganciphisa induna, kodwa hhayi njalo. Uma uzama ukukhulelwa, noma kunjalo, ukulawulwa kokubeletha bekungeke kube yindlela yokwelashwa okuhle. Amanye ama-acne treatments awaphephile angasetshenziswa uma uzama ukukhulelwa, ngakho qiniseka ukuthi utshele udokotela wakho uma uzama ukukhulelwa.
Kulabo abazama ukukhulelwa, ukwelashwa kwe-PCOS kufana nezokwelapha ezisetshenziselwa ukwelashwa. Umzila wokuqala wezokwelapha ngokuvamile u- Clomid , osetshenziselwa ukusiza ukugqugquzela ukuvota.
I-Metformin- eyaziwa nangokuthi i-Glucophage-iyisidakamizwa esivame ukusetshenziswa ukuphathwa kwe-insulin ukumelana. Ngezinye izikhathi lisetshenziselwa ukuphatha i-PCOS, ngisho noma ungenayo ukumelana ne-insulin.
I-Letrozole-imithi yomdlavuza-ngezinye izikhathi isetshenziselwa kude-ilebula ukuze kukhuthazwe i-ovulation. Isebenza ngendlela efanayo nendlela uComomid enza ngayo. I-Letrozole ingaba yimpumelelo kakhulu ekusizeni abesifazane abane-PCOS ukukhulelwa kune-Clomid.
Uma le mithi ingasiza, khona-ke i- gonadotropins ingase ivivinywe. Lezi yimithi yokwelapha engenayo.
Uma imithi yodwa ingasebenzi, noma uma kunezici eziningi eziholele ekusaneni , i- IUI noma i- IVF yokwelapha inganconywa .
Ucwaningo oluthile lubonise ukuthi abesifazane abakhuluphele ngokweqile nge-PCOS bangakwazi ukuqala kabusha i-ovulation ngokwemvelo ngokulahlekelwa ngamaphesenti ayishumi kuphela esisindo sabo samanje . Ukudla okunempilo nokuvivinya umzimba njalo kungasiza ukubuyisela ukuvuthwa okuvamile kwabanye, kodwa hhayi bonke, abesifazane abane-PCOS.
Ingabe Ukukhulelwa Nge-PCOS Noma Yimuphi Ohlukile?
Abesifazane abane-PCOS banengozi enkulu yokuthola izinkinga ezithile zokukhulelwa. Abesifazane abane-PCOS banamathuba amaningi okuthuthukisa isifo sikashukela sokukhulelwa, ukukhulelwa okuhlobene nokucindezelwa kwegazi eliphezulu, preeclampsia, kanye nokuqala komsebenzi. Amantombazane azalwa nabesifazane abane-PCOS anengozi eyengeziwe yokudinga ukunakekelwa kwe-NICU ngemuva kokuzalwa.
Isizathu salezi zingozi zingase zivele ukukhuluphala okuhlobene ne-PCOS noma ukumelana ne-insulin. Indlela engcono kakhulu yokunciphisa lezi zingozi ukufinyelela isisindo esinempilo (noma enempilo) ngaphambi kokukhulelwa (uma kungenzeka), qiniseka ukuthi uthole ukunakekelwa kokubeletha okuvamile, futhi udle ukudla okunempilo. Yiqiniso, ungenza zonke izinto ezifanele futhi usabhekene nezinkinga.
Imithombo:
> Barbieri, uRobert; U-Ehrmann, uDavid. Ukubonakaliswa kwemitholampilo ye-polycystic syndrome ye-ovary kubantu abadala. Kusesikhathini.
> Barbieri, uRobert; U-Ehrmann, uDavid. Ukuxilongwa kwe-polycystic ovary syndrome kubantu abadala.
> Fauser BC1, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, Carmina E, Chang J, Yildiz BO, Laven JS, Boivin J, Petrlia F, Wijeyeratne CN, Norman RJ, Dunaif A, Franks S, Wild I-RA, i-Dumesic D, i-Barnhart K. "Ukuvumelana ngokuphathelene nezempilo zebesifazane ze-polycystic ovary syndrome (i-PCOS): i-Amsterdam ESHRE / ASRM-Exhasiwe i-PCOS Consensus Workshop Group. "Fertil Steril. 2012 Jan; 97 (1): 28-38.e25. doi: 10.1016 / j.fertnstert.2011.09.024. I-Epub 2011 Dec 6.