Ukuqonda Izinga eliphezulu le-Testosterone e-Men and Women

by URachel Gurevich; Kubukezwe ngu-Anita Sadaty, MD

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Izinga le-testosterone emadodeni nakwabesifazane ngesikhathi i-TTC

I-Testosterone ibalulekile ekukhiqizeni kanye nokuphila kahle kokubili kokubili kokubili amadoda nabesifazane. Amazinga aphansi angabangela ukukhathala kokubili abesilisa. UCharles Knox / Getty Images

Ukuhlolwa kwezinga le-Testosterone yingxenye ebalulekile yokuhlolwa kokuzala. Nakuba i-testosterone ivame ukubhekwa njengendoda "yamadoda", i-testosterone ibalulekile kubo bobabili impilo yebesilisa nabesifazane.

Kodwa, njengezo zonke i-hormone, awudingi kancane noma kakhulu.

Emadodeni, i-testosterone ephansi iyimbangela engabangela ukungabi nabantwana. Kodwa-ke, ungase umangale ukuzwa ukuthi amazinga aphezulu e-testosterone angaba yinkinga futhi.

Kwabesifazane, amazinga aphezulu e-testosterone angabonisa inkinga yokuzala. Abesifazane bangaba namazinga aphansi e-testosterone, kodwa lokhu kwenzeka ngemuva kokuya esikhathini sokuphumula futhi hhayi njengokuvamile phakathi neminyaka yokubeletha.

Yini eyenza amazinga aphezulu noma aphansi e-testosterone kumadoda nabesifazane? Ngaphezu kwalokho, yini engenziwa ngakho, ikakhulukazi uma uzama ukukhulelwa?

Qhubeka ufunda. Okokuqala, ake sixoxe ngamazinga aphansi e-testosterone emadodeni, awaziwa nangokuthi u-hypogonadism wesilisa. A

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Izimpawu Zamazinga Ephansi E-Testosterone Emadodeni

I-libido ephansi kanye nokungasebenzi kahle kwe-erectile yizimpawu zamanqanaba aphansi e-testosterone. Umthombo wesithombe / i-Getty Izithombe

I-testosterone ephansi iyaziwa nangokuthi i-hypogonadism yesilisa. Ubuchopho besilisa bungabangela ukungabi nabantwana.

Udokotela wakho angase acabange ukuthi amazinga wakho we-testosterone aphansi kakhulu uma ...

Amazinga wakho wamahhala we-Testosterone angaphansi kuka-9 ng / dL
Amazinga wakho we-Testosterone wakho angaphansi kuka 240 ng / dL

Izimpawu ze-testosterone ephansi emadodeni zingafaka ...

Ukungenzi lutho
Ukucindezeleka
Ukukhathala
Ukuncipha kwesisindo somzimba
Ukunciphisa intshebe nokukhula kwezinwele zomzimba
I-low sex drive
Ukungasebenzi kwe-Erectile
Amabele akhulisiwe noma azwelayo
Amandla anciphile
Ukushisa okushisayo
Kunzima ngokuhlushwa

U-hypogonadism wesilisa oyinhloko yilapho inkathazo iqhamuka kuma-testes. Lokhu kungabuye kubhekiselwe ekuhlulekeni kwe-testicular eyinhloko noma ekunqumeni kwamadoda. Eqinisweni, ezinye zezimpawu zifana nokuqeda umama wesifazane.

I-hypogonadism yesilisa yesibili yilapho inkathazo ivela emgodini we-pituitary noma i-hypothalamus. Lezi zingqungquthela ebuchosheni zikhiqiza ama-hormone ama-FSH ne- LH , okukhomba ukuthi ama-testes akhiqiza i-testosterone.

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Izimbangela ze-Testosterone ephansi eMadodeni

Ukukhuluphala uma imbangela yokuvimbela isifo esiphansi se-testosterone emadodeni futhi ingaba nethonya elinamandla kunokuguga. UDavid Zaitz / Getty Images

Ezinye izimbangela zamazinga aphansi e-testosterone kumadoda afaka ...

Ubudala : Uma amadoda efinyelela eminyakeni yobudala engama-50, amazinga e-testosterone aqala ukwehla kwemvelo. Ukuzala komuntu kuyancipha ngeminyaka yobudala , nakuba kungenjalo njengoba kubonakala kubesifazane.

Ukukhuluphala : Ukukhuluphala kungase kube nomthelela omkhulu kunamazinga e-testosterone kuneminyaka yobudala. Ucwaningo lithole ukuthi ukunyuka kwesisindo kuhlobene ngokuqondile namazinga we-testosterone. Ukulahlekelwa isisindo kungaletha amazinga wakho we-testosterone.

Ukubhema : Ukubhema kubuye kwandisa ingozi yokuntula ingane .

Ukuba nesisindo esiphansi : Amazinga e-BMI angavamile, ukungondleki nokuzivocavoca ngokweqile kungaholela emazingeni aphansi e-testosterone futhi wehla ukuzala.

I-Klinefelter syndrome (KS) (XXY) : Lokhu kuyisifo sezakhi zofuzo lapho esikhundleni sokuba ne-X eyodwa ne-Y chromosome eyodwa, le ndoda ine-X eyengeziwe ye-chromosome. Yimbangela evamile yokungasebenzi komuntu.

I-Kallmann syndrome : Lesi yisimo sezakhi zofuzo lapho ukukhulelwa kungaphumeleli ukuqala noma kungagcwalisi.

Ukuphazamiseka kwe-Pituitary : lokhu kuhlanganisa nezinkinga nendlela umsebenzi we-pituitary. Kungaba ngumphumela wesifo se-pituitary noma isisu sobuchopho. Noma, ukwelashwa kwe-tumor yobuchopho nemisebe kungabangela umonakalo wesikhathi eside i-pituitary.

Amathambo angenakhulunywa : lokhu kuvamise ukuxazulula ngesikhathi sokuqala. Uma kungenjalo, kufanele kulungiswe. Uma kungenjalo, kungabangela izinkinga ze-hormonal kamuva ekuphileni.

Amazinga aphakeme kakhulu ensimbi : Lokhu kwaziwa nangokuthi i-hemochromatosis.

Ukulimala kobufakazi : Uma kwenzeka umonakalo owodwa we-testicular, ukukhiqizwa kwe-testosterone kungase kuvamile.

Ukwelashwa komdlavuza : Ukwelashwa kwe-Chemotherapy kanye nokwelashwa kwemisebe kungaphazamisa okwesikhashana testosterone futhi kuphazamise ukukhiqizwa kwesidoda. Nokho, ngezinye izikhathi umonakalo unomphela. Ucwaningo olulodwa lathola ukuthi amadoda angama-30% anamazinga aphansi e-testosterone ngemuva kokwelashwa.

I-HIV / AID : igciwane lingaphazamisa indlela umsebenzi we-testes, we-pituitary, ne-hypothalamus. Lokhu, futhi, kungaholela emazingeni aphansi e-testosterone.

Ukugula okukhulu noma ukuhlinzwa : Lokhu kuzovame ukuguqula ngokwakho emva kwesikhathi sokuphumula. Ezinye izifo, njengama-mumps, zingabangela izinkinga zesikhathi eside ze-hormonal.

Ukusetshenziswa kwezidakamizwa zezokwelapha noma zokuzilibazisa : Ngokwesibonelo, inambuzane ingabangela amazinga aphansi e-testosterone.

Amazinga aphezulu kakhulu okucindezeleka : Amazinga aphezulu we-hormone yokucindezeleka i-cortisol aye ahlotshaniswa namazinga aphansi e-testosterone.

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Ukwelapha Izinga Eliphansi le-Testosterone Emadodeni

Udokotela wakho anganikeza i-testosterone engenayo ukuthuthukisa amazinga akho nokuzala kwakho. Tom Merton / Getty Izithombe

Uma amazinga akho aphansi e-testosterone engumphumela wesimo esithile esingokwempilo noma isimo sokuphila (njengokukhuluphala), okungenani ingxenye yocwaningo lwakho lwezokwelapha lizophatha isimo sokuqala.

Kungenzeka kulezi zimo ukuba amazinga e-testosterone abuyele kumazinga avamile emva kokwelashwa noma ukuguquka kwendlela yokuphila.

Lokhu akuyona inketho njalo, ngeshwa.

Kulezi zimo, udokotela wakho angancoma eyodwa, enye, noma konke okulandelayo:

I-testosterone supplementation : Udokotela wakho angase anikeze i-testosterone engenayo. Lokhu kuzokwenza ukuthi ngokuqinisekisiwe kukhuliswe umkhiqizo wesilisa.

I-testosterone supplementation ingabuye ibekwe ukuze kuthuthukiswe inhlalakahle yakho kanye nempilo ejwayelekile, ngisho noma ingeke ixazulule inkinga yokuzala.

I-Clomid : Nakuba iningi livame ukuhlotshaniswa nokungabi nabesifazane, i- Clomid ingasetshenziswa nasemadodeni ukuthuthukisa ama-testosterone.

Ukwelashwa kwe-IVF : I- IVF ingasetshenziswa kanye noma esikhundleni se-supplementation ye-hormone.

Uma kukhona izici zokuzala ezithintekayo, udokotela wakho angase futhi ancoma ukuthi uzama i-IVF kuqala.

I-IVF ne-ICSI : Nge- IVF-ICSI , i-sperm ngayinye igxilwe ngqo eqenjini.

Isiqalo se-sperm testicular (TESE) : Uma isibalo se-sperm esincane noma akukho isibalo sesidoda sinenkinga, udokotela wakho angase asikisele ukukhishwa kwesidumbu se-testicular (TESE) . Lokhu kuhilela ukuthola i-sperm ngokuqondile kusuka ku-testes nge-biopsy.

Isibelethi sobudlova : Kwezinye izimo, udokotela wakho angancoma ukusebenzisa umnikezeli wesilisa.

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Izimpawu Nezizathu Zamazinga Aphezulu E-Testosterone Emadodeni

Amazinga aphezulu e-testosterone angabangela ingozi eyengeziwe yokuthatha ukuziphatha. ftwitty / Getty Izithombe

Amazinga e-testosterone aphezulu kakhulu ayaziwa nangokuthi i-hypergonadism.

Udokotela wakho angacabanga ukuthi amazinga wakho we-testosterone aphakeme kakhulu uma ...

Amazinga wakho we-testosterone angaphezu kuka-950 ng / dL
Amazinga wakho we-testosterone mahhala angaphezu kuka-30 ng / dL

Izimpawu ezibonakalayo nezibonakaliso ze-testosterone ephakeme zihlanganisa ...

Ukukhulelwa kwasekuseni, kumadoda amasha
Ukungabi nalutho nokunciphisa isibalo sododa
I-acne
I-libido ephezulu
"Ukuphunga" ngokweqile "
Umfutho wegazi ophezulu
Ukubala kwesibalo esiphezulu segazi
Ukwandisa ukuziphatha okuyingozi
Ukucindezela

Amazinga aphezulu e-testosterone angabangelwa ...

Izicubu: Izicubu ezinama-adrenal and testicular zingabangela u-testosterone ophakeme ngokungavamile.
Ukuhlukunyezwa kwe-anabolic steroid: Ngesinye isikhathi esetshenziswa ngabadlali nabakhi bomzimba ukwakha ubuningi besisindo noma ukwandisa ukusebenza kwezemidlalo. Abanye abagijimi bathatha i-Clomid ukukhulisa ukusebenza, ngokungemthetho.
I-testosterone supplementation: Ngezinye izikhathi enqunywe udokotela, futhi ngezinye izikhathi ithengwa ngokungemthetho ngaphandle kwemithi.
Ukuxhumana nomuntu osebenzisa i-gel testosterone. I-gel ingabhekwa ngengozi komunye umuntu, ikhulise amazinga awo e-testosterone ngokungenhloso.

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Ukwelapha Izinga Eliphezulu Lama Testosterone Emadodeni

Ungase ucabange ukuthi u-testosterone ngaphezulu usho ukuzala okuphezulu, kodwa awusebenzi kanje. Peter Dazeley / Getty Images

Kuyinto engavamile ukuba amazinga e-testosterone aphakanyiswe kancane angabangela ukungabi namuntu emadodeni. Kodwa-ke, uma amazinga ephakeme ngokungavamile, umbuzo uzoba ukuthi ngabe ubangelwa isisu (esingavamile) noma ngokusetshenziswa kwezidakamizwa.

Uma kungenxa yokusebenzisa i-anabolic steroid noma i-testosterone supplementation, ukusekela ama-supplements noma i-steroids kufanele ixazulule le nkinga. Lokhu kufanele kwenziwe ngaphansi kokuqondiswa udokotela.

Kuyamangaza amadoda amaningi ukuthi i-testosterone ephezulu ingabangela ukungabi nabantwana. Amanye amadoda athatha izithako ze-testosterone ezicabanga ukuthi zizokwenza ngcono ukuzala kwazo. Noma, bayithatha benethemba lokuthuthukisa amandla abo, amandla namandla.

Ngeshwa, ukwesekwa kwe-testosterone emadodeni abangayidingi ngemithi kungabangela ukungasebenzi.

Ucwaningo olulodwa lwathola ukuthi kwamadoda athatha izithako ze testosterone futhi awadinga, 88.4% yizo azoospermic. Ngamanye amazwi, abazange bakhiphe nhlobo isilwane.

Kodwa-ke, ezinyangeni eziyisithupha ngemuva kokumisa isisindo se-testosterone, ama-65% wamadoda ayengekho azoospermic. Baqala ukukhiqiza isidoda futhi.

Amadoda akuzona kuphela okudingeka akhathazeke ngamazinga e-testosterone.

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Izinga eliphezulu le-Testosterone eliphansi kwabesifazane

Abesifazane abanamazinga aphezulu e-testosterone bangase bahlangane nokukhula kwezinwele ebusweni, okungaba nzima ngokomzwelo. Westend61 / Getty Izithombe

Uma kuziwa ekuzameni ukukhulelwa, kwabesifazane, i-testosterone ephakeme ngokuvamile yinkinga kune-testosterone ephansi kakhulu.

I-testosterone ingenye yamahomoni amaningana eyaziwa ngokuthi i-androgens. Amazinga aphezulu a-androgen abesifazana ayaziwa ngokuthi hyperandrogenism.

Izimpawu zamazinga aphezulu a-androgen afaka phakathi ...

Izikhathi ezingavamile
Anovulation
I-acne
Ukukhula kwezinwele okungavamile
Ukulinganisa iphathini lamadoda
Izwi elijulisayo
Ukwanda komzimba we-muscle
I-clitoris ekhulisiwe

Izimbangela ezikhona zamanqanaba aphakeme e-testosterone kubesifazane zifaka:

I-PCOS: I- Polycystic ovarian syndrome iyimbangela evamile yokungabi nabantwana kubafazi . I-PCOS ibuye ihlotshaniswe nokukhuluphala nokunciphisa i-insulin.
I-congenital adrenal hyperplasia (CAH): Lesi simo sezakhi zofuzo eziphazamisa izigulane zakho ezingaphezu kokukhiqiza ama-hormone abalulekile. Kungabangela ukungabi nabantwana kumadoda nabesifazane. Abanye besifazane bayotholakala ukuthi bangabantwana. Ngezinye izikhathi, kungenzeka kamuva ekuphileni. Lokhu kwaziwa ngokuthi iqala ukuphumula noma i-congréital adrenal hyperplasia (CAH).
Amagciwane e-adrenal noma ama-ovarian: amazinga aphezulu kakhulu e-testosterone angaphezu kuka-200 ng / dL angabonakala ezimweni zomdlavuza.
Ukusetshenziswa kwe-Anabolic Steroid: Abagijimi besilisa abayena kuphela abasebenzisa kabi i-steroids ukuthuthukisa ukusebenza. Abesifazane abahlukumeza i-steroids bangase babe namazinga aphezulu kakhulu e-testosterone.

Kuthiwani nge-testosterone ephansi kwabesifazane?

Abesifazane abanamazinga aphansi we-testosterone bangathola ...

I-libido ephansi
Ukucindezeleka
Ukukhathala
Izinkinga zokuqonda

I-testosterone ephansi kwabesifazane ivame ukubonakala ngesikhathi sokuya esikhathini kodwa kungenzeka nganoma yisiphi isikhathi. Amazinga e-Testosterone wehla kanye ne-estrogen nezinye amahomoni okuzala. I-testosterone ephansi akuyona inkinga kubesifazane abazama ukukhulelwa.

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Ukwelapha izinga le-Testosterone elingavamile kwabesifazane

Ukuzivocavoca, ukudla, nokunciphisa umzimba kungasiza ukunciphisa amazinga e-testosterone, ikakhulukazi ngosizo lwe-metformin. I-Cultura RM / JPM / Getty Images

Lapho ukwelapha amazinga aphezulu e-testosterone, udokotela wakho uzocabangela imigomo yakho nezimpawu zakho. Ukwelashwa kuhlukile uma uzama ukukhulelwa.

Isibonelo, ukwelashwa okukhona kungukuthi amaphilisi okulawula ukubeletha , kodwa lokho akufanelekile kumuntu ozama ukukhulelwa.

Okunye kungenzeka ukuthi i-spironolactone yezidakamizwa ezilwa no-androgen (igama lomkhiqizo u-Aldactone.) I-Spironolactone ayiphephile ukuthatha uma ikhulelwe, ngakho akufanelekile kulabo abazama ukukhulelwa.

Izinketho kwabesifazane abanethemba lokuba nomntwana zihlanganisa:

Ukulahlekelwa isisindo nokuzivocavoca : Ukulahlekelwa isisindo esiningi nokuvivinya umzimba njalo, ikakhulukazi kwabesifazane abane-PCOS, kungasiza amazinga e-testosterone aphansi futhi angase aqale kabusha ukuvuthwa.

I-Metformin : Ukwelapha ukuvimbela i-insulin ngesifo sikashukela se- metformin singasiza ukunciphisa izimpawu ze-PCOS nokuqala kabusha ukuvunguza.

Imithi yokwelapha : Ngokuqinisekile uzodinga kokubili ukuguqulwa kokuphila kanye nemithi yokuzala yokukhulelwa. I-Clomid ne- letrozole yizona zokwelapha zokuqala zokuzala kwabesifazane abane-PCOS.

Imithi yokwelapha : Kwabesifazane abazama ukukhulelwa, ukwelapha izimonyo okufana nokweqa noma ukuxuba kungase kube nezixazululo zokukhula kwezinwele okungadingeki.

Ungathola kanjani ukhulelwe nge-PCOS

Okunye ngezimbangela zokungasebenzi:

_Imithombo:

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_{Groth KA1, Skakkebæk A, Høst C, Gravholt CH, Bojesen A. "Ukubuyekezwa komtholampilo: Klinefelter syndrome - ukuvuselelwa kwemitholampilo." J Clin Endocrinol Metab.} _{2013 Jan; 98 (1): 20-30.} _{doi: 10.1210 / jc.2012-2382.} _{I-Epub 2012 Nov 1. http://www.ncbi.nlm.nih.gov/pubmed/23118429/}

_{I-Howell SJ1, i-Radford JA, i-Ryder WD, iShalet SM.} _{"Umsebenzi we-testicular ngemuva kwe-cytotoxic chemotherapy: ubufakazi bokungasebenzi kahle kwe-Leydig." J Clin Oncol.} _{1999 May; 17 (5): 1493-8.} _{http://www.ncbi.nlm.nih.gov/pubmed/10334536/}

_{Høst C, Skakkebæk A, Groth KA, Bojesen.} _{"Indima ye-hypogonadism ku-Klinefelter syndrome." U-Asian J Androl.} _{2014 Mar-Apr; 16 (2): 185-91.} _{i-doi: 10.4103 / 1008-682X.122201.} _A1. _{http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955327/}

_{Kumar P, Kumar N, Thakur DS, Patidar A. I-hypogonadism yamadoda: Izimpawu nokuphathwa.} _{I-Journal of Advanced Technology Mithi Technology & Research .} _{2010; 1 (3): 297-301.} _{doi: 10.4103 / 0110-5558.72420.} _{http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255409/}

_{I-Surampudi P1, i-Swerdloff RS, i-Wang C. "Ukubuyekezwa kwindlela yokwelapha yesilisa." Uchwepheshe we-Opin Pharmacother.} _{2014 Jun; 15 (9): 1247-64.} _{i-doi: 10.1517 / 14656566.2014.913022.} _{Epub 2014 Apr 23. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168024/}

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