Okumele Ukulindele: Ukwelashwa, Imiphumela Ehlangothini, Nemiphumela Yempumelelo
Ungase ucabange nge- Clomid njengesiyaluyalu semithi yokuzala - kanti kuyiqiniso ukuthi i-FDA kuphela iyakwamukela ukwelashwa kwabantwana abangenasifazane. Kodwa i-Clomid ingasetshenziselwa ukuphatha amanye amacala okungazalwa komuntu . Lezi zimo zibhekwa njenge "off-label" ukusetshenziswa.
Sibutsetelo
I-Clomid ingasiza ukuzala komuntu ngezindlela ezimbalwa. Kungasiza ukukhulisa amazinga wokubala kwesidoda nokulungisa ukungalingani kwe-hormonal.
Kungakusiza futhi ukuba ugweme i- IVF noma ukwelashwa okuhlinzekwayo. Kwezinye izimo, kungasiza ukukhulisa izinkinga zakho zokuphumelela ngemuva kokuhlinzwa noma ngesikhathi se-IVF.
Uma uzibuza ukuthi i-Clomid ingakusiza yini, thatha isikhathi sokuhlola izinga layo lempumelelo nemiphumela emibi engenzeka. Ngale ndlela ungenza isinqumo esifundisiwe futhi unikwe amandla futhi ube nengxoxo enkulu nodokotela wakho.
Izinkomba
Udokotela wakho angabeka uComomid ezimweni ezilandelayo.
Unamazinga aphansi e-testosterone.
Ngenkathi amadoda ephathwa nge- testosterone ephansi ngokuvamile ezwa ukungabi nabantwana, udokotela wakho angacabangela ngokukhethekile ukubeka i-Clomid uma amazinga aphansi ngenxa ye-hypogonadropic hypogonadism. Ngisho noma ungazami ukuba nomntwana, uComomid angasiza ngezimpawu ze-hypogonadism, kufaka phakathi:
- Ukungasebenzi kwe-Erectile
- Nciphisa ukukhula kwezinwele zomzimba
- Nciphisa ubukhulu besisipha
- Ukukhathala
- I-libido ephansi
- Inkinga ngokuhlushwa
- Ukushisa okushisayo
Uthola ukuthi une-oligoasthenozoospermia idiopathic.
Izindlela ze- Idiopathic ezibangelwa imbangela engaziwa. U-Oligoasthenozoospermia kusho ukubalwa kwesidoda esiphansi kanye nompofu wesilisa ompofu.
Uma ukuhlaziywa kwesilisa kutholakala ukuthi unesibalo esincane se-sperm kanye nomoya oswelekile , kodwa udokotela wakho akakwazi ukuchaza ukuthi kungani unenkinga, angase akuthole i-oligoasthenozoospermia idiopathic.
I-Clomid iyinye inketho yokwelapha okungenzeka.
Uthola ukuthi une-azoospermia engeyona i-nonobstructive.
I-Azoospermia kusho ukuthi ayikho isidoda esitholakalayo emzimbeni. Izindlela ezingavinjelwe akukho ukuvinjelwa ngokomzimba okuvimbela isidoda ukuba singene ejaculate.
Nge-azoospermia, i-Clomid ingahle ibekwe ukuze kusize ukudala nokwandisa isibalo sowesilisa. Ngisho noma lokho kungaphumeleli, i-Clomid ingandisa ukwanda kwe-sperm extraction noma i-testes biopsy (yilapho amasosha omzimba amancane athathwa khona nge-needle ngokuqondile kusuka ku-testes, bese ekhula emvelweni webhu).
Une-varicocele.
Esinye sezimbangela ezivame kakhulu zokungazalwa kwamadoda yi- varicoceles . A varicocele kuyinto veic varicose in the scrotum noma testes.
Kungabaza ukuthi ngabe ukuhlinzwa noma i-Clomid iyindlela yokwelapha engcono kakhulu. Ukwelashwa kubonakala kukhulisa impilo yeningi jikelele ngaphezu kwe-Clomid, kodwa yikuphi ukwelashwa okungenzeka ukwandise izimo zakho zokukhulelwa akucacile. Ngokuya ngobudala bomlingani wakho wesifazane nokuthi ngabe unezinkinga zokuzala, udokotela wakho angase asikisele ukuzama ukwelashwa kwe-Clomid kuqala. Khona-ke, uma ungaphumelelanga, ungakhetha ukuba ne-varicocelectomy (ukuhlinzwa ukukhipha i-varicocele).
Isilinganiso Nokuphathwa
Ukwelashwa kwe-Clomid yamadoda akufani nokwelashwa kwabesifazane abangenasifo.
Abesifazane bathatha i-Clomid cishe izinsuku ezinhlanu ngezinsuku ezithile zenyanga. Uma isebenza, i-Clomid ithuthukisa ukuzala komfazi ngale nyanga.
Ukwelashwa kwamadoda akusebenzi kanje. Ngamadoda, i-Clomid ivame ukuthathwa izinsuku ezimbalwa okungenani izinyanga ezintathu. Kuthatha isikhathi esiningi ukubona imiphumela, futhi akufanele ulindele ukuthuthukiswa okusheshayo kokuzala. Ukwelashwa ngokuvamile kuthatha okungenani inyanga ngaphambi kokuba noma yikuphi ukushintshwa kwenzalo kungabonwa, futhi izinyanga ezintathu ezigcwele ngaphambi kokukhula kokukhulelwa kungabonisa ngcono.
Kufanele njalo ulandele imiyalelo kadokotela wakho ngenkathi uthatha i-Clomid. Ama-protocol ambalwa ajwayelekile asetshenziswayo afaka:
- Isilinganiso sama 25mg esithathwe nsuku zonke izinsuku ezingu-25, silandelwa yisikhathi sokuphumula sezinsuku ezinhlanu. Lo mjikelezo uphindwa izinyanga ezintathu.
- Isilinganiso se-25mg esithathiwe izinsuku ezinhlanu, kulandelwa izinsuku ezinhlanu, ngezinyanga ezintathu.
- Isilinganiso esiphakeme sama-100mg athathwe izinsuku ezingu-10, kanye ngenyanga, izinyanga ezintathu.
Udokotela wakho angase anike i-antioxidant ukuthatha nge-Clomid. Ama-antioxidants afana ne-vitamin E aboniswe ukuthuthukisa impumelelo yokwelapha. Udokotela wakho angase futhi ahlele umsebenzi wegazi ngezikhathi ezithile ukuze ahlole amazinga akho e-testosterone. Angahle ahlele ukwelashwa kwakho ngokusekelwe emiphumeleni.
Okuqhamuka uma udla imishanguzo
Ucwaningo oluningi lwe-Clomid namadoda alutholanga imiphumela emibi kakhulu. Lokhu akusho ukuthi imiphumela emibi kakhulu ayinakwenzeka, kuphela ukuthi uma eyenzayo, akuvamile.
Imiphumela Ebizayo Engaphezulu
Umbono ophuphuthekile ungumphumela omubi ongase ube nawo, ngoba ungadala futhi ungabangela umonakalo wombono unomphela uma ushiywe ungaphenduliwe. Uma uhlangabezana nokuphazamiseka kombono noma ukuphazamiseka kombono ngenkathi uthatha i-Clomid, xhumana nodokotela wakho ngokushesha.
Imiphumela emibi engakhululekile
Akukho ulwazi oluthe xaxa olutholakalayo emiphumeleni engeyona engathà sina kepha engakakhululekile ye-Clomid emadodeni. Lokhu kungenxa yokuthi ucwaningo lokuqala luqhutshwa kuphela ezigulini zesifazane.
Ngokuvamile, iningi lemiphumela emibi ebonwayo kwabesifazane ibangelwa izinguquko ze-estrogen. Ngenxa yokuthi amazinga e-estrogen emadodeni aphansi kunabesifazane, amadoda angaphansi kwamathuba okuba nemiphumela emibi kakhulu engabhekana nayo nabesifazane.
Ucwaningo olulodwa lwathola ukuthi amaphesenti angu-5 ezakhamuzi zesilisa abhekana nesisindo sezinyosi. Kwabesilisa abathile, ububele buhamba ngokuzenzekelayo ngesikhathi sokwelapha. Kwabanye, kwaqhubeka kuze kube yilapho ukwelashwa kuphelile.
Ingabe I-Clomid Ukwelashwa Kwamadoda Kuyokwandisa Ingozi Yamawele?
Cha, i-Clomid ayinakwandisa ubungozi bamawele uma kuthathwa ukungazalwa komuntu. Lapho abesifazane bethatha i-Clomid, kukhulisa i-ovulation. Lokhu kungaholela ekubeni namaqanda amabili akhululwe esikhundleni sodwa. Uma amaqanda amabili evuliwe futhi boba bobabili baqala ukukhulelwa, owesifazane angakhulelwa ngamawele.
Emadodeni, i-Clomid ikhulisa isibalo sembewu kanye nempilo. Isibungu esingaphezulu asiholeli ekwandeni kwamawele.
Izindleko Zempumelelo Impumelelo Yomuntu
Impumelelo ingachazwa ngezindlela ezimbili ezahlukene:
- Ukuthuthukiswa kwamanqanaba ezempilo kanye ne-testosterone
- Izinga lokukhulelwa landa
Uhlobo luni lokukhulelwa ongalulindela? Isilinganiso sokukhulelwa esiphakathi siphezulu ngamaphesenti angu-13 kuya kwangu-15, futhi ezifundweni ezibandakanya imibhangqwana ebhekene nokungasebenzi komuntu, amazinga wokukhulelwa emva kokuphathwa kwe-Clomid kuyahlukahluka.
Okushiwo Ucwaningo
Ucwaningo oluthile kodwa oluthakazelisayo lwathola ukuthi i-Clomid, kanye ne-antioxidant treatment (efana ne-vitamin E), iphakamisa kakhulu izinga lokukhulelwa ngamaphesenti angama-36.
Ukuhlaziywa kwesinye se-meta kubheka imiphumela yezifundo eziningana ku-Clomid nokungazalwa kwamadoda, ikakhulukazi, amadoda abhekene nenani le-sperm low and / noma umsoco wesilisa ompofu. Ithole ukuthi ukwelashwa ne-Clomid, uma kuqhathaniswa nokungenawo ukwelashwa, kwanda ukuhlushwa kwesidoda ngamaphesenti angaba ngu-5 kanye nokuthuthukiswa kwesimo sempilo ngamaphesenti angaba ngu-4.
Amazinga we-hormone okukhiqiza nawo aphuthukisiwe kakhulu nge ukwelashwa kwe-Clomid, ngamazinga e-FSH akhula amazinga angu-4 jikelele kanye nama-testosterone aphakama ngamaphesenti angu-54.
Amadoda abhekene ne-Azoospermia
Akusilo isidoda esitholakalayo embonini nhlobo.
Kwesinye isifundo, uComomid wasiza abantu abangu-64.3 ukuba bakhiqize umuthi, ngokuhlaziywa kwamademoni imiphumela ebonisa phakathi kwesigidi esisodwa nesigidi esingu-16 nge-milliliter.
Kula madoda angazange akhiqize isidoda emva kokwelashwa kwe-Clomid, zonke iziguli ezikulesi sifundo zinezidakamizwa ezanele zokubuyiselwa ngokusebenzisa isisindo se-spermtic spermular. Isidakamizwa esivele singasetshenziselwa ukwelashwa kwe- ICSI-IVF .
Izwi elivela ku- Verywell
Kwezinye izimo, udokotela wakho uzobeka i-Clomid ngezizathu ezithile ngaphandle kokungasebenzi. Kungakhathaliseki ukuthi kunjalo yini, qiniseka ukuthi uqonda imiphumela emibi engaba khona kanye nomsebenzi ohlangene nodokotela wakho ukuze ulandele indlela yokwelashwa enqunyiwe. Ngale ndlela uzobona ephephile futhi cishe imiphumela emihle kakhulu.
Uma kwenzeka uthatha i-Clomid ukuthuthukisa ukuzala, ingakunika wena nomlingani wakho ithemba. Khumbula ukuthi isimo sakho siqu sizoxhomeka ekuzaleni kwakho nokuzala komlingani wakho, ngakho ungazizwa udangele uma i-Clomid ingasebenzi. Phinda futhi, chaza ucwaningo futhi usebenze ngezandla nodokotela wakho ukuze uhlole izinketho zakho.
> Imithombo:
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> George B1, Bantwal G. "Ukuphathwa kwe-Endocrine kokudlulela kwamadoda. "I- Indian J Endocrinol Metab . 2013 Oct; 17 (Suppl1): S32-S34.
> Ghanem H1, Shaeer O, El-Segini A. "Ukwelapha i-clomiphene citrate kanye ne-antioxidant therapy for infertility ye-idiopathic yesilisa: isilingo esilawulwa ngokungahleliwe. " Fertil Steril . 2010 Meyi 1; 93 (7): 2232-5. doi: 10.1016 / j.fertnstert.2009.01.117. Epub 2009 Mar 6.
> Katz DJ1, Nabulsi O, Tal R, Mulhall JP. "Imiphumela yokuphathwa kwe-clomiphene citrate kuma-young hypogonadal. " BJU Int . 2012 Aug; 110 (4): 573-8. i-doi: 10.1111 / j.1464-410X.2011.10702.x. Epub 2011 Nov 1.
> Patankar SS1, Kaore SB, Sawane MV, Mishra NV, Deshkar AM. "Umphumela we-clomiphene citrate ngobuningi bomdlandla kubalingani besilisa bomshado ongenasifo. " Indian J Physiol Pharmacol . 2007 Apr-Jun; 51 (2): 195-8.