Indlela Ukwelapha Ngayo Ukwelashwa Ekukhuliseni Amangcwaba E-Preemie
Lapho ingane isengozini yokubeletha ngaphambi kwesikhathi , udokotela uzovame ukunikeza umama uchungechunge lwemijovo ye-steroid ukuze kusize ukuthuthukiswa kwamaphaphu emntanini. Ebhekwa njengendlela yokwelashwa kwe-steroid yangaphambi kokubeletha, inqubo iyasebenza ngokuphumelelayo ekunciphiseni ingozi yokubhekana nezinkinga ezisongela ukuphila, kuhlanganise nokuphefumula kwesifo somzimba (RDS) .
I-Betamethasone noma i-dexamethasone yi-steroids emibili esetshenziswa kakhulu ezimweni zokubeletha kwangaphambi kokubeletha, ijowe okungenani amahora angu-24 ngaphambili futhi ingabi ngaphezu kweviki ngaphambi kokuzalwa komntwana. Ukwelashwa okushiwo ochungechungeni lwezibhamu ezimbili kuhambisane namahora angu-24.
Indlela i-Antenatal Steroids isebenza ngayo
I-Steroids, ebizwa ngokufanele ngokuthi i-corticosteroids, iyindlela yokwenziwa kwamahomoni angokwemvelo asetshenziselwa ukunciphisa ukuvuvukala. Uma isetshenzisiwe ngokungenakulinganiswa, lesi sidakamizwa sithunyelwa kumntwana ngegazi legazi lomama kanye nokusiza ekukhuliseni amaphaphu wengane ngezindlela ezimbili ezibalulekile:
- Ukwandisa ukukhiqizwa kwama- surfactants , ingxube ye-lipids namaprotheni akhiqizwa ngumzimba, okwehlisela ukungezwani komzimba emaphashini futhi kwenza kube lula ukuphefumula.
- Iyanciphisa uketshezi emaphashini, okuqhubeka nokusiza ekuphefumuleni ngokwandisa umthamo wamaphaphu.
Uma izijovo zinikezwa ngaphezu kweviki ngaphambi kokuzalwa, imiphumela ijwayele ukuguquka futhi ingase iguqule izinzuzo zokwelashwa.
Ngenxa yokuthi ayinakwazi ukubhekana nezifundo eziningi , kubalulekile ukuba isikhathi sokujola kufane nesiteji esinqunyiwe ngangokunokwenzeka.
Imiphumela Ezingenakwenzeka
Ucwaningo oluningi luphetha ngokuthi ukusetshenziswa kwe-antenatal steroids akubanga neze ukulimala kwesikhashana kwengane. Ngenkathi bekukhona ukusikisela okunye ukuthi lo mkhuba wawuxhunyaniswe nokungahleleki (ukukhula kwamafutha omzimba nesisindo) ezinganeni, iningi locwaningo lalinganiselwe ezinhlobonhlobo zezilwane.
Ucwaningo olunyatheliswa kuyi-June 2017 lwe-Research Pediatric Research lwaluphikisana nesimangalo, okuphetha ngokuthi phakathi kwabangu-186 abaneminyaka engu-14 ubudala ababelethwe ngaphambi kwesikhathi-abanye babo bebezitholele izidakamizwa zesifo sokubeletha kanye nabanye ababengakaze babe khona izibalo umehluko ngesilinganiso sokungafani phakathi kweqembu ngalinye.
Ngalokho kuthiwa, enye yemiphumela emibi kakhulu yokusetshenziswa kwesifo sokubeletha kwesifo sokubeletha isisindo sokuzalwa esincane , evame ukuhambisana nabantwana abaye bavezwa kwi-corticosteroids engaphezu kweyodwa. Ubuningi bobufakazi bamanje bubonisa ukuthi izingane ezivezwe emithinini eminingi zinengozi engamaphesenti angama-300 enkulu wesisindo somzimba esincane futhi akukho miphumela engcono noma embi kakhulu uma kuqhathaniswa nezingane ezivezwe inkambo eyodwa.
Kuwo wonke amacala ambalwa, izingane ezisezingeni eliphansi lokuzala izothola "ekubambeni" ngenkathi ziyizingane ezincane ezingathinteki ekuthuthukiseni noma ekuthuthukiseni imoto.
Ngokufanayo, abukho ubufakazi bokuthi i-steroids yokubeletha ingalimaza umama (ngaphandle kwalokho, mhlawumbe, ngokubangela ubuhlungu bendawo noma ukuvuvukala endaweni yomjovo). Okukuphela kwalaba besifazane abaye bafunda izifundo eziningi, abambalwa ababebikezele izinkinga zokulala zesikhashana.
> Imithombo:
> I-American College ye-Obstetrics ne-Gynecologists. "I-ACOG Committee Opinion: I-Antenatal Corticosteroid Therapy of Fetal Maturation." I-Obstetrics ne-Gynecology. 2017; 130 (2): e102-e109. I-DOI: 10.1097 / AOG.0000000000002237.
> Washburn, L .; I-Nixon, i-P .; Snively, B. et al. "I-corticosteroids yokuzalwa kwangasese kanye nemiphumela ye-cardiometabolic ezincane ezizalwa ngesisindo esiphansi kakhulu." Ucwaningo lwezingane. 2017; 82-107. I-DOI: 10.1038 / pr.2017.133.