Ukwelapha, Izimbangela, Ukuxilongwa, Nezinketho ZokuKhaya Komndeni
Ukungasebenzi kahle kwama-ovarian (i-POI) kuyimbangela engabangela ukungabi nabesifazane . Eyaziwa nangokuthi ukuhluleka kwe-ovarian ngaphambi kwesikhathi, abesifazane abano-POI abavuni njalo futhi abakwazi ukukhulelwa ngamaqanda abo. Ukukhetha kokwelashwa okuphumelela kunazo zonke ukwelapha i-IVF ngeqanda noma umnikelo wombungu.
Abesifazane abane-POI babhekana nezibonakaliso zemitholampilo kanti ngezinye izikhathi izimpawu zokuya esikhathini sokuzalwa ngaphambi kweminyaka engu-40.
(Isilinganiso seminyaka yokunqamuka kwesikhashana siphakathi kuka-48 no-55.) Lesi sifo singase sibhekwe njenge-hygongonadotropic hypogonadism (HH) noma i-hypogonadism eyinhloko.
I-POI ayikona ukuya esikhathini. Ngenkathi lesi sifo sasibizwa ngokuthi "ukuyeka isikhathi eside ngaphambi kwesikhathi," leli gama alinembile.
Abesifazane abaye bafika esikhathini sokuya esikhathini abazuzi isikhathi, abakwazi ukuvota, futhi abakwazi ukukhulelwa ngamaqanda abo.
Abesifazane abane-POI bangase bavame ukuvota futhi bangase babe nokubuyela esikhathini sokuya esikhathini (ngisho neminyaka emva kokuxilongwa). Futhi, ukukhulelwa ngamaqanda abo siqu akunakwenzeka ngokuphelele. (Okuningi ngalokhu ngezansi.)
Ukungasebenzi kahle kwe-ovarian akuyona imbangela evamile yokungasebenzi, kodwa akuvamile. Ingozi yokuxilongwa ikhula ngokukhula:
- Abangu-1 ku-1 000 abesifazane abaneminyaka engu-15 kuya ku-29 batholakala ukuthi banePPI
- 1 ku-250 kwabesifazane abaneminyaka engama-30 kuya ku-35
- 1 ku-100 kwabesifazane abaneminyaka engu-35 kuya ku-40
Ukuthola ukuxilongwa kwe-primary ovarian insufficiency kungaba yingozi kakhulu.
Uma udokotela wakho ekutshela ukuthi izinkinga zakho zokuba nengane ephathelene nezakhi zofuzo zingenakwenzeka, ungase uzizwe udidekile, uthukuthele, futhi udabuke kakhulu. Ungase uzizwe uhlazekile futhi ungenathemba. Ekuqaleni, ungase uzizwe unganandaba noma udidekile.
Lezi imizwa evamile ukuba nayo .
Uma uthola lokhu okuxilongwa, sicela ucele ukusekela.
A
Xoxa nodokotela wakho, udokotela owaziwa ngokungazalwa , futhi, uma kunokwenzeka, iqembu lokusekela kwabantwana , ngakho-ke ungadabukisa futhi uhlole ngokugcwele izinketho zakho.
Ngesikhathi sokuphulukiswa, kungenzeka ukuba ube nokuphila okugcwele nokujabulisayo nokungaqiniseki okuyinhloko kwe-ovarian.
Kungani Kulukhuni Ukubona Ukuntuleka Okukhulu Kwe-Ovarian?
Ama-ovari womfazi omdala onempilo aqukethe amashumi ezinkulungwane ze-follicles . In follicle ngayinye liyiqanda elikhona . Iphesenti elincane kuphela lala follicle lizohlala livuthiwe, livuthwe, futhi likwazi ukuba umbungu.
Kungokwemvelo futhi kuvamile ukuba izintambo ziwehlise ngesikhathi.
Icala ngephutha, intombazane enempilo izalwa enamaqanda angaphezu kwezigidi eziyi-1. Kodwa ngesikhathi esifinyelela eminyakeni eyishumi nambili, uzobe esehle kuze kube ngu-300,000 kuphela.
Kuyinto evamile ukuba izintambo zigcine ukuyeka ukusabela ngokuphumelelayo kumahomoni adala ukukhula kwamaqanda nokuvunguza. Lesi sizathu sokwehluleka okuhlobene nobudala , nokuthi kungani abesifazane abaneminyaka engama-40 nangaphezulu bengenakho ukukhulelwa kunomfazi oneminyaka engu-30 ubudala.
Kodwa-ke, kulaba besifazane abanamaphutha okuqala e-ovarian, ama-ovari awo awasebenzi ngendlela elindelekile.
Ama-ovari angase abe nezintambo ezimbalwa kunalokho okungalindelwe owesifazane oneminyaka yakhe.
Isibalo sabo se- antral follicle (indlela yokulinganisa isamba esiphelele sama-follicles atholakalayo kuma-ovari) azoba ngaphansi.
Futhi, ama-ovari nama-follicle ngeke aphendule kahle ama-hormone okuhloswe ukugqugquzela ukuvuthwa kwamaqanda nokuvuthwa. Ama-ovaries angase ahluleke ukukhiqiza amazinga ajwayelekile e-estrogen.
Yingakho izidakamizwa zokuzala azisebenzi kahle kubesifazane abane-POI.
Izidakamizwa zokuzala ziyosebenza kuphela uma kunezintuthwane ezanele ezitholakala kuma-ovari ukuze zivuselelwe futhi uma lezo follicles zizophendula uma zivezwa ngama-hormone-okuvuselela ama-ovulation.
Ku-POI, i-follicles "ayizinaki" noma okungenani ayiphenduli ngokugcwele emithini yokuzala.
I-Clomid noma i- gonadotropin ngokuvamile ayiphumeli ukugqugquzela ukuthuthukiswa kwamaqanda okunempilo noma ukuvunguza.
Ngisho noma zingabangela ukuvunguza, amaqanda angase abe yizinga elibi. Lokhu kwenza ukukhulelwa kanye nokukhulelwa kube lula.
Izimpawu Zokuntuleka Okuvamile Kwe-Ovarian
Ukungasebenzi kahle kwe-ovarian okuyinhloko yinkinga ye-spectrum. Ezinye izimo ze-POI zimbi kunabanye.
Lokhu kusho nokuthi abesifazane bazoba nezimpawu ezihlukahlukene zezimpawu.
Uphawu oluvame kakhulu yizikhathi ezingavamile. Abesifazane abanePPI bangase
- Awunaso isikhathi (amenorrhea)
- Yiba nezikhathi eziza njalo (ngaphezu kwezinsuku ezingama-35)
- Yiba nezikhathi eziza ngokungavamile (zihluka okungaphezu kwezinsuku ezimbalwa kusukela ngenyanga kuya enyangeni)
- Yenza ukuphuma esikhathini okungavamile (izikhathi ezincane kakhulu noma ukuphawula)
Kungenzeka futhi ukuthi owesifazane onama-POI ahambe ngaphandle kwemijikelezo ejwayelekile yokuya esikhathini, bese ngokuzumayo aqale ukuya esikhathini.
Abanye, kodwa hhayi bonke, abesifazane abano-POI abanezimpawu ezivela emazingeni aphansi e-estrogen. Lezi zimpawu zingase zibe njalo noma zize zihambe.
Lezi zimpawu zingabandakanya:
- Ubulili obubuhlungu
- Ukomisa kwamagagasi
- I-libido ephansi
- Ukushisa okushisayo kanye / noma ukujula ebusuku
- Ukuqwashisa noma ubunzima bokulala
- Ukucindezeleka kanye / noma ukukhathazeka
Uma unemijikelezo engavamile, kodwa unayo lezi zimpawu eziphansi ze-estrogen, ingabe lokho kusho ukuthi awunawo i-POI?
Akunjalo ngempela.
Phakathi kwamaphesenti angu-50 no-75 abesifazane abano-POI bayodonsa bese bekhulula isrogen ngezikhathi ezithile.
(Lokhu akufani nomfazi oye wangena esikhathini sangempela. Ngemva kokumisa isikhashana, i-ovulation namazinga e-estrogen wangaphambi kokumama ayitholakali nhlobo.)
Kodwa-ke, ngaphambi kokuba ukhathazeke, kunezimbangela eziningi ezingabangela ukuvuthwa okungavamile noma okungekho .
Amaphesenti angaphansi kwezingu-10 kwabesifazane abane-anovulation azotholakala ene-POI.
Izimbangela ezivame kakhulu zokuvuthwa okungavamile zihlanganisa i- polycystic ovarian syndrome (i-PCOS) , i-hyperprolactinemia, nokungasebenzi kokuhlobene nokukhuluphala ngokweqile .
Ukuhlolwa kobubele nokwenza ukutholakala kokuntuleka okuphezulu kwe-Ovarian
Ukuxilongwa kwe-primary ovarian insufficiency ayikwazi ukwenza izimpawu zodwa.
Kukhona nezinye izimbangela ezingezansi zomjikelezo kanye namazinga aphansi e-estrogen, ngaphandle kokungasebenzi kahle kwe-ovarian.
Udokotela wakho angalawula ukuhlolwa okulandelayo ngaphambi kokuxilongwa:
- Ukuhlolwa kokukhulelwa (ukuqinisekisa ukuthi akusikho ukuthi izikhathi zakho ziye zayeka)
- Amazinga e-FSH (azoba ngamanqamu okumisa phambili nge-POI)
- Amazinga e-Estradiol (estrogen) (ngokuvamile aphansi kwabesifazane abane-POI, kodwa hhayi njalo)
- I-AMH (ukuhlola yonke indawo yokugcina ama-ovarian )
- Iprolactin (ukulawula i-hyperprolactinemia)
- I-Antral follic count count (i-ultrasound, futhi ukuhlola ama-ovarian reserves)
- Ukuhlolwa kwenselele ye-Clomid (ukuhlola ukuthi ama-ovari akho asabela kanjani emithini yemithi yokuzala)
Uma amazinga akho e-FSH aphezulu ngokungavamile nakwehlu lwamadoda, udokotela wakho cishe uzohlehlisa kabusha ukuhlolwa inyanga ngemva kwesikhathi ukuqinisekisa.
Uma imiphumela iphinda, futhi uneminyaka engama-40 noma encane, udokotela wakho angase akubone ukuthi ukhona ne-POI.
Yini Ebangela Ukuntuleka Okuyinhloko Kwe-Ovarian?
Kubaningi besifazane abane-POI, ngeke kwaziwa ukuthi yini eyabangela i-syndrome.
Ukungakwazi ukusebenza kwama-ovarian okuyinhloko kuhlotshaniswa nezifo eziningi ezizimele, kuhlanganise nesifo somzimba esomile, isifo se-rheumatoid, ne-lupus. Noma kunjalo, indlela abahlobene ngayo ayifuni.
Ezinye izimo ze-POI zibangelwa ukuguqulwa kwezakhi zofuzo. I-Fragile-X ne- Turner syndrome ingabangela i-POI.
Kodwa-ke, ucwaningo olusha lwezakhi zofuzo luye lwabona ukuthi amacala angama-20 kuya kwangu-25 amaphesenti angu-POI angabangwa yizici zofuzo (kuhlanganise ne-Fragile-X ne-Turner syndrome.)
Lokhu kusesimweni sokuqala socwaningo, ukuhlola okunembile okwamanje akutholakali okwamanje. Esikhathini esizayo, noma kunjalo, ukuhlolwa kofuzo kungakwazi ukuqhubeka nokukhomba labo abasengozini.
Njengoba kunikezwe ukuxhumeka kofuzo okungenzeka, akumangazi ukuthi umlando womndeni we-ovarian insufficiency oyinhloko uvele ngamaphesenti angu-10 kuya kwangu-15 amacala.
Akukwazi ukuthi ngabe abesifazane abane-primary ovarian insufficiency bazalwa ngamaqanda ambalwa noma uma ukuzala kwabo kwehla ngokushesha.
Ukwehluleka kwama-ovarian okuyinhloko nakho kungabangelwa ukwelashwa.
Eminye imithi yokwelashwa, kuhlanganise ne-chemotherapy, imisebe, nokuhlinzwa, ingaholela ku-POI.
Ukungakwazi kahle kwe-ovarian eyinhloko eyenzeka ngokushesha ngemva kokuba ukwelashwa kwaziwa ngokuthi ukwehluleka kwe-ovarian.
Kubalulekile ukwazi ukuthi ukunciphisa ukuzala ngemva kokuphathwa komdlavuza akuhlali njalo. Kungakhathaliseki ukuthi ukuzala kwakho kuzobuya ngokuyinhloko noma ngokugcwele kuzoxhomeka kuneminyaka yakho lapho uthola ukwelashwa komdlavuza nokuthi yiziphi izindlela zokwelashwa zomdlavuza ezisetshenzisiwe.
Uma uthola ukuthi unomdlavuza, futhi ungakaqali ukwelashwa komdlavuza, khuluma nodokotela wakho mayelana nokulondoloza ukuzala kwakho. Kungenzeka ukuthi ukhiphe amaqanda akho noma izicubu zomzimba .
Ukwelapha Ukwelashwa Kwe-Primary Ovarian Insufficiency
Ukukhetha ukwelashwa okungcono kakhulu futhi okuvame ukwelashwa kuphela kwabesifazane abanokukhubazeka okuyinhloko okuyi-primary ovarian i- IVF neqanda noma umsizi wombungu.
Uma ngaphezu kwe-POI kunezinkinga ze-uterine, i- surrogate nayo ingadingeka ukuze ithwale ukukhulelwa. Kodwa lokhu akuvamile.
Iqanda noma umnikeli wombungu kungenzeka abe ngumnikeli owaziwayo noma ilungu lomndeni-kodwa kaningi, umnikeli akaziwa. Umtholampilo wakho wokuzala ungakusiza uthole i-egg donor, noma ungase usebenze nebhange noma i-ejensi.
Umnikeli wombungu angalungiswa ngomtholampilo wakho wokuzala noma i-ejensi.
Qaphela kakhulu izikhangisi ze-intanethi kanye nezinhlinzeko ze-egg noma umnikelo wombungu. Kukhona abantu ngaphandle lapho befuna ukuhlukumezeka abazali abalahlekelwe yimali yabo.
I-IVF ene-egg donor iphumelela kakhulu. Eqinisweni, i-egg donor IVF inezinga eliphezulu kakhulu lokuphumelela kukho konke ukwelashwa kwe-IVF .
Ucwaningo olulodwa lwathola ukuthi abesifazane abaqedile imijikelezo emithathu ye-IVF ngamaqanda abanikela ngemali babenezithuba ezingamaphesenti angama-90 okukhulelwa.
Izindleko yisithiyo esikhulu kunawo wonke ama-egg donor IVF.
Umjikelezo omusha we-egg donor ungase ube phakathi kuka- $ 25,000 kuya ku-35,000. Uma ucabanga ukuthi kungadingeka wenze imijikelezo eminingi, izindleko zingashesha kakhulu.
Ukusebenzisa amaqanda afriziwe kusuka ebhange laseqanda kungabiza kancane, njengoba "kungabelana" nge-egg donor nomunye umbhangqwana. Enye indlela yokunciphisa izindleko ukuba nomuntu owaziwayo-umnikeli, njengomngane noma ilunga lomndeni.
Noma kunjalo, umjikelezo kungenzeka usaba ngu-$ 15,000 kuya ku-20,000 uhla.
I-IVF ye-Embryo i-IVF ayibiza kakhulu, futhi ishibhile kune-IVF evamile.
Ngokusho kwe-RESOLVE, umjikelezo wesilinganiso sombukeli embrini emtholampilo wokuzala ubiza phakathi kuka- $ 2,500 no-4,000.
Noma kunjalo, leyo mali ayihlanganisi imithetho kanye nokululekwa kwengqondo okudingekayo. Imali ingase ibe ngaphezulu uma ihlelwe nge-ejensi.
Amanani okuphumelela ngeminikelo yombungu ehlukahluka kakhulu. Kuzoxhomekeka emtholampilo wokuzala, isimo sokuzala kombhangqwana owanikela ngemibungu, futhi noma yiziphi izici ezibelethwayo zingase zibe yidlala kuwe.
Ukwenza isinqumo sokusebenzisa iqanda noma umnikeli wombungu kungaba ngokomzwelo futhi kunzima. Ukuvuma ukuthi ngeke ukwazi ukuthola inzalo yesifo sangasese kungaba kubi kakhulu.
Ukukhetha umhlinzeki wombungu kusho ukuthi bobabili wena nomlingani wakho ngeke nibe ne-genetically ehlobene nengane. Ngomnikelo wamaqanda, kuphela wena ngeke ube nokuhlotshaniswa ngokofuzo.
Ukwelulekwa ngophrofayli ohlangene nezindaba zokuzala akukhuthazwa kakhulu kuphela kodwa futhi kuyadingeka imitholampilo eminingi ngaphambi kokuqala ukwelashwa.
Ngingakwazi yini ukukhulelwa ngamaqanda ami? Ingabe Ngidinga Ukusebenzisa I-Egg Donor?
Abesifazane abaye baphethwe ukwelashwa komdlavuza bangakwazi ukusebenzisa amaqanda noma imibungu yabo uma bethatha izinyathelo zokulondoloza ukuzala kwabo ngaphambi kokwelashwa. Lokhu kungenzeka ukuthi kwakunjengokuqanda amaqanda (vitrification) , ama-ovarian tissue frozen, noma ama-cryopreservation embryo.
Futhi, abanye besifazane abathola i-POI ngemuva kokwelashwa komdlavuza bangase babuye umsebenzi we-ovarian.
Uma uzama ukukhulelwa emva komdlavuza, khuluma nodokotela wakho mayelana nezinketho zakho.
Uma ungazange uqhubeke nokulondolozwa kokuzala ngaphambi kokuba uhlolwe, ukukhulelwa ngamaqanda akho akunakwenzeka.
Nokho, akunakwenzeka.
Ucwaningo luye lwathola ukuthi amaphesenti angu-5 kuya kwengu-10 kwabesifazane abathintekayo abanesifo sokuphefumula okuyisisekelo sama-ovarian baye baqala ukukhulelwa, ngezinye izikhathi ngokuzenzekelayo.
Lokhu kungahle kwenzeke noma ngaphandle kwemithi yokuzala. Kubonakala sengathi kuvame kakhulu kubantu besifazane abathola ukwelashwa kwe-hormone (okuhloswe ukubhekana nezimpawu eziphansi ze-estrogen ze-POI.)
Abanye besifazane bangena ekuxoxweni okwesikhashana futhi kungenzeka ukuthi ama-ovari azoqala ukusebenza futhi. Kungenzeka ukuthi ukujikeleza kwabo ukubuyela esikhathini ngemva kweminyaka eminingi engavamile noma engekho.
Akuqondakali kahle ukuthi kungani abanye besifazane bethola ukuthethelelwa noma ukukhulelwa kanti abanye abakwenzi.
Udokotela wakho akakwazi ukubikezela ukuthi lokhu kuzoba yisimo sakho. Uma ufuna ngempela ukuba nengane, enethemba lokuthi uzowela eqenjini lucky 5 kuya kwezingu-10 iqembu akulona uhlelo oluhle.
Kukhona ubufakazi bokuthi abanye besifazane abane-POI bangakwazi ukugcoba nokukhulelwa ngamaqanda abo uma bethola isrogen ukwelashwa ngaphambi kokusetshenziswa kwezidakamizwa zokuzala.
Ukucwaninga ngale ndlela-ukwelashwa kwe-estrogen okulandelwa ukwelashwa nge-gonadotropins -wathola imiphumela ehlanganisiwe.
Nakuba izifundo ezimbalwa zithole impumelelo ethile, abanye abazange baphumelele.
Khumbula ukuthi izinga lokuphumelela lemithi yokuzala, i- IUI , noma i- IVF ngamaqanda akho aphansi kakhulu.
Njengoba kunikezwe izindleko zokwelashwa, kanye nokucindezeleka ngokomzwelo kwemijikelezo yokwelapha engabonanga, ukuhamba ngqo kwi- IVF ngamaqanda omnikelo noma imibungu kungase kube ukuhamba okuhlakaniphile kakhulu.
Yiqiniso, thola umbono wesibili. Ungahambi ngqo ku-IVF nge-egg donor ngaphandle kokubonisana nodokotela abangaphezu kweyodwa.
Kodwa-ke, awufuni nokuchitha izinsiza zemali nezomzwelo zokwelapha ezingenakwenzeka ukuphumelela.
Qaphela: uma ungafuni ukukhulelwa, futhi une-POI, akufanele uthembele kumaphilisi okulawula ukubeletha okuvamile (noma ukuhlolwa kwesifo sokubeletha) ngokukhulelwa kweso. Amaphilisi okulawula ukubeletha awafundwanga kwabesifazane abanalesi sifo.
Abesifazane abane-POI baye bakhulelwa ngamaphilisi okulawula ukuzalwa kanye nokwelashwa kwe-hormone.
Uma ufuna ukugwema ukukhulelwa, indlela yokuvimbela noma idivayisi ye-intrauterine ingaba ngcono.
Okukhethwa kukho okuhlukile ngaphandle kwe-Fertility Treatment
Ngenkathi i-IVF eneqanda noma i-embryo donor kungenzeka ukhethe ukwelashwa okuyinhloko kokwelashwa kwakho, akuyona nje ukhetho lomndeni wakho kuphela.
Eminye imibhangqwana isinqumo sokuphishekela ukukhuliswa noma ukukhulisa izingane. Bangase bacabange ukutholwa kwabantwana kusukela ekuqaleni, noma bathuthele ekutholeni uma ukwelashwa kwehluleka.
- Izindlela Ezi-15 Zokuwenza Umehluko Ekuphileni Kwengane
- Izizathu Ezi-8 Zokuthi Ungalandele Ukwelashwa Kwenzalo Noma IVF
Ukukhetha ukuphila okungenayo ingane kuyindlela eyengeziwe.
Umeluleki angakusiza ukuba ucabangele zonke izinqumo zakho, ngakho ungenza isinqumo esinolwazi.
Ukuhlolwa okungeziwe (okungewona okuzala) emva kokuthola ukuxilongwa kwe-POI
I-POI ihlotshaniswa nezinye izinkinga zempilo. Ngenxa yalesi sizathu, udokotela wakho angalawula ukuhlolwa okuqhubekayo, kubandakanya:
Ukuhlolwa kwesisindo samathambo : Amazinga e-estrogen aphansi akubeka engozini ye-osteoporosis. Ukwelapha ama-hormone, ukudla okunempilo, nesisindo sokusebenzisa umzimba kunganciphisa ingozi yakho.
I-Karyotype nokuhlolwa kofuzo : Ezinye izimo ze-POI zibangelwa ukuguqulwa kwesakhi. Abanye besifazane bangenayo i-X-chromosome eyodwa kuphela kunokubili.
Ukuvivinya nge-genetic kungabuye kuhlolwe igciwane le-FMR1, elihlobene ne-Fragile X syndrome ne-POI.
Amahomoni e-thyroid : Abesifazane abane-POI basengozini yokungalingani kwe -roid. Empeleni, phakathi kwamaphesenti angu-14 no-27 abesifazane abano-POI nabo bazoba nesifo se-low.
I-Cortisol level noma i-corticotropin (ACTH) yokuhlola ukugqugquzela : Abesifazane abane-POI basengozini yokubhekana nezinkinga ze-grenal adrenal.
Ucwaningo luye lwabona ukuthi cishe amaphesenti amathathu kwabesifazane abanesifo esiyinhloko se-ovarian abangakwazi ukuthuthukisa isifo sika-Addison.
Ukuhlola ngokuzenzakalelayo : Kufika kuma-20 amaphesenti abesifazane abano-POI bazobhekana nezinye izifo zokuzivikela.
Abesifazane abane-primary ovarian insufficiency bangaphezu komphakathi jikelele ukuba babe nalezi zinkinga zezempilo ezengeziwe, kodwa awunikelwe zona.
Njengoba njalo, khuluma nodokotela wakho uma unemibuzo noma ukukhathazeka.
Impilo Engokomzimba Nokwengqondo Ngemva kokuthola ukuxilongwa kwe-POI
Abesifazane abanamazinga aphansi okuthiwa yi-estrogen basengozini enkulu yesifo senhliziyo, ubunzima obuncansi ( kubandakanya ubulili obubuhlungu ), kanye ne-osteoporosis.
Enye yokwelashwa okungase kube khona udokotela wakho angancoma ukuthi ukwelashwa kwe-hormone esikhundleni. Ngokuvamile inhlanganisela ye-estrogen ne-progesterone, lokhu kunganciphisa ezinye zezibonakaliso zakho futhi kunganciphisa ingozi ye-osteoporosis.
I-hormone therapy ingasiza futhi ngokushisa okushisayo nomoya ophansi ohlobene ne-estrogen ephansi.
Ukwelashwa kuvame ukuqhubeka kuphela kuze kube seminyaka yobudala bokunqamuka kwesikhashana, lapho kungavamile ukuba ne-estrogen ephansi.
- Ukwelashwa kwe-Estrogen for "Ukuya esikhathini sokuqala esikhathini sokuqala"
Njengawo wonke ukwelashwa, kunezingozi nezinzuzo ezingenzeka.
Akekho owazi ngempela ukuthi izingozi zesikhathi eside zingakanani ukwelashwa kwama-hormone (noma ukungenzi ukwelashwa kwe-hormone) kwabesifazane abane-POI.
Xoxa ngezinketho zakho zokwelashwa nodokotela wakho.
Abesifazane abane-primary ovarian insufficiency bangase babe nokucindezeleka kanye / noma ukukhathazeka .
Lokhu kuyingxenye ngenxa yezinga eliphansi le-estrogen, kodwa futhi, ukuxilongwa kanye nokuphelelwa yisisu kungabangela ukucindezeleka ngokomzwelo . Uma kunezinkinga ze-adrenal noma ze-thyroid, lezi zingabangela nomoya ophansi.
Ukululekwa kuhlelwe kakhulu. Uchwepheshe wezokwelapha, ikakhulukazi ojwayele ukungasebenzi, angakusiza ukuba ubhekane nokuxilongwa futhi wenze izinqumo ezinolwazi mayelana nezinketho zokwakha umndeni wakho.
I-anti-depressant ingase ibe usizo. Ungacabangi ukuthi awukwazi ukuthatha enye uma uzama ukukhulelwa. Lokhu kuyinto yokuxoxa nodokotela wakho wokuzala, udokotela oyinhloko wokunakekela, nomeluleki.
> Imithombo:
> Umnikelo wesibindi: Izinganekwane namaqiniso. HLELA: I-National Infertility Association. Ifinyelele ngo-Julayi 27, 2016.
> Nelson, Lawrence M. Ukubonakaliswa Kwemitholampilo nokuHlola kokungasebenzi kahle kwe-Ovarian Primary (Ukwehluleka kwe-Ovarian ngaphambi kwesikhathi). UptoDate.com.
> Nelson, Lawrence M; I-Calis, i-Karim Anton. "Ukuphathwa Kwezinga Eliphansi Lokungasebenzi Kwe-Ovarian (Ukwehluleka Kwama-Ovarian Okwedlule). "UptoDate.com.
> Nelson LM. Ukungakwazi ukusebenza kwe-Ovarian Primary. I-New England Journal of Medicine. 2009; 360 (6): 606-614. i-doi: 10.1056 / NEJMcp0808697.
> Qin Y1, Jiao X1, Simpson JL2, Chen ZJ3. "I-Genetics of Primary Ovarian Insufficiency: Ukuthuthukiswa Okusha Nezikhundla." Ukuhlaziywa kwe-Hum Reprod . 2015 Nov-Dec; 21 (6): 787-808. i-doi: 10.1093 / i-humupd / dmv036. Epub 2015 Aug 4.